St Louis, MONCT05446272Now EnrollingIRB Ready

Extubation Failure Clinical Trial in St Louis, MO

Access cutting-edge extubation failure treatment through this clinical trial at a research site in St Louis. Study-provided care at no cost to qualified participants.

Sponsored by University of Pennsylvania

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Expert Care in St Louis

Access extubation failure specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related extubation failure treatment provided free

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Check if you qualify for this extubation failure clinical trial in St Louis, MO

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to St Louis

    Convenient for MO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit St Louis site if eligible
  4. 4Begin participation

About This Extubation Failure Study in St Louis

DIVA is a pragmatic randomized clinical trial (RCT) to determine: among (P) preterm infants born 23 0/7-28 6/7 weeks gestation undergoing extubation from mechanical ventilation, whether (I) Non-invasive neurally adjusted ventilatory assist (NIV-NAVA) (C) compared with Non-synchronized nasal intermittent positive pressure ventilation (NS-NIPPV), will reduce the incidence of (O) extubation failure within (T) 5 days (120 hours) of extubation.

Sponsor: University of Pennsylvania

Who Can Participate

Inclusion Criteria

Gestational age of 23 0/7- 28 6/7 weeks at birth
Intubated in the first 7 days of life
Undergoing extubation following at least 12 hours of invasive mechanical ventilation
Post-natal age \<32 weeks Post menstrual age at time of extubation

Exclusion Criteria

Major congenital anomalies, including pulmonary hypoplasia
Neurologic disorders affecting respiratory drive (other than apnea of prematurity)
Esophageal bleeding or other contraindication to NG/OG catheter placement
Current weight \<500 grams (based on Edi catheter approval)
Study ventilator not available at time eligibility criteria are met
Planned surgery or invasive procedure within 5 days of extubation
Informed consent not provided

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in St Louis?

Yes, this clinical trial (NCT05446272) has an active research site in St Louis, MO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Extubation Failure Treatment Options in St Louis, MO

If you're searching for extubation failure treatment options in St Louis, MO, this clinical trial (NCT05446272) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our St Louis research site is actively enrolling participants for this clinical trial. You'll receive care from experienced extubation failure specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all extubation failure clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · St Louis, MO