Glenview, ILNCT03249337Now EnrollingIRB Ready

Fuchs' Endothelial Dystrophy Clinical Trial in Glenview, IL

Access cutting-edge fuchs' endothelial dystrophy treatment through this clinical trial at a research site in Glenview. Study-provided care at no cost to qualified participants.

Sponsored by Marian Macsai, MD

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Expert Care in Glenview

Access fuchs' endothelial dystrophy specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related fuchs' endothelial dystrophy treatment provided free

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Check if you qualify for this fuchs' endothelial dystrophy clinical trial in Glenview, IL

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Why Participate?

  • No-Cost Study Care

  • Local to Glenview

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Glenview site if eligible
  4. 4Begin participation

About This Fuchs' Endothelial Dystrophy Study in Glenview

In brief, the objective of this study is to investigate whether the drug Glanatec ® which is approved in Japan for glaucoma and ocular hypertension, can be used in patients with Fuchs endothelial dystrophy who have had a descemet stripping procedure without endothelial keratoplasty. While some limited data exists as a proof of concept in in vitro or animal studies, and Glanatec® has been successfully used in a recently published case series for this indication, there is insufficient data to show that this drug can be effectively used for corneal cell clearing while maintaining patient safety. The goal of the study is to provide sufficient proof of concept for the use of this drug in patients with FED whose only treatment alternative is to undergo corneal transplant.

Sponsor: Marian Macsai, MD

Who Can Participate

Inclusion Criteria

• Ability to understand read and sign the informed consent form.
Age between 30 and \<91 years
Ability to understand and follow instructions and study procedures
Willingness to comply with all study procedures and be available for the duration of the study
Ability to apply eye drop medication and willing to adhere to study medication regimen
Diagnosed with Fuchs dystrophy (clinically and on confocal microscopy) by the study investigator.
Pseudophakic FED with posterior capsule supported, suture-fixated, or sulcus-supported posterior chamber intraocular lens.
Fuchs dystrophy grades 2-4 on the Krachmer grading scale
Presence of central guttae deemed by the investigator to be the chief cause of visual symptoms, rather than cataract or corneal stromal edema
Clear peripheral cornea with an endothelial cell count \>1000 cells/mm2 on specular microscopy
Best corrected visual acuity in the study eye is 20/40 or worse at study enrollment
The patient is dissatisfied with current vision
The patient is otherwise to be offered a corneal graft
For females with reproductive potential, willingness to use highly effective contraception (e.g., hormonal contraception, barrier contraception, intrauterine device, or abstinence).
Indication for surgery may include cataract extraction and posterior chamber intraocular lens implantation

Exclusion Criteria

• Uncontrolled glaucoma (IOP \>25 mmHg)
Presence of secondary corneal pathology such as infective or autoimmune keratitis
Advanced corneal stromal edema defined as the presence of haze, bullae, or DM folds on slit-lamp biomicroscopy
History of herpes simplex virus or cytomegalovirus keratitis
Prior endothelial keratoplasty
Aphakic in study eye.
Allergy to any component of the Ripasudil hydrochloride hydrate 0.4% that will be used in the course of the study
For women of child-bearing potential: Pregnant or lactating, or planning to become pregnant within the next 6 months.
Any other ocular condition that, in the opinion of the investigator, may preclude the subject from study participation.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Glenview?

Yes, this clinical trial (NCT03249337) has an active research site in Glenview, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Fuchs' Endothelial Dystrophy Treatment Options in Glenview, IL

If you're searching for fuchs' endothelial dystrophy treatment options in Glenview, IL, this clinical trial (NCT03249337) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Glenview research site is actively enrolling participants for this clinical trial. You'll receive care from experienced fuchs' endothelial dystrophy specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all fuchs' endothelial dystrophy clinical trials near you to find additional studies recruiting in your area.

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