Aurora, CONCT06655246Now EnrollingIRB Ready

Gastrointestinal Stromal Tumor (GIST) Clinical Trial in Aurora, CO

Access cutting-edge gastrointestinal stromal tumor (gist) treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by Kura Oncology, Inc.

Quick Self-Assessment

See if you qualify for this Aurora location

Preparing your pre-screening questions…

Expert Care in Aurora

Access gastrointestinal stromal tumor (gist) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related gastrointestinal stromal tumor (gist) treatment provided free

Apply for This Aurora Location

Check if you qualify for this gastrointestinal stromal tumor (gist) clinical trial in Aurora, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Gastrointestinal Stromal Tumor (GIST) Study in Aurora

In this clinical trial, the safety, tolerability, and preliminary antitumor activity of ziftomenib in combination with imatinib will be evaluated in adults with gastrointestinal stromal tumors (GIST) who have been treated previously with imatinib.

Sponsor: Kura Oncology, Inc.

Who Can Participate

Inclusion Criteria

Documented diagnosis of advanced/metastatic KIT-mutant GIST.
Documented disease progression on imatinib as current or prior therapy.
Eastern Cooperative Oncology Group (ECOG) performance status of ≤2 at screening.
At least 1 measurable lesion per RECIST v1.1 modified for GIST.
Negative pregnancy test for participants of childbearing potential.
Adequate organ function per protocol requirements.
Resolution of all clinically significant toxicities from prior therapy to \<Grade 1 (or participant baseline) within 1 week before the first dose of study intervention.
Participant, or legally authorized representative, must be able to understand and provide written informed consent before the first screening procedure. Key

Exclusion Criteria

Diagnosis of GIST without a KIT mutation or with a T670X KIT mutation.
History of prior or current cancer that has potential to interfere with obtaining study results.
Received a prohibited medication, including investigational therapy, less than 14 days or within 5 drug half-lives before the first dose of study intervention.
Active central nervous system metastases.
Uncontrolled intercurrent illness, including, but not limited to protocol defined cardiac disease.
Mean corrected QT interval (QTcF) greater than 470ms.
Left ventricular ejection fraction (LVEF) \<50%.
Major surgery within 2 weeks before the first dose of study intervention.
Is pregnant or breastfeeding.
Gastrointestinal abnormalities that may impact taking study intervention by mouth.
Actively bleeding, excluding hemorrhoidal or gum bleeding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT06655246) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Gastrointestinal Stromal Tumor (GIST) Treatment Options in Aurora, CO

If you're searching for gastrointestinal stromal tumor (gist) treatment options in Aurora, CO, this clinical trial (NCT06655246) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced gastrointestinal stromal tumor (gist) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all gastrointestinal stromal tumor (gist) clinical trials near you to find additional studies recruiting in your area.

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