Ann Arbor, MINCT06785116Now EnrollingIRB Ready

Gestational Hypertension Clinical Trial in Ann Arbor, MI

Access cutting-edge gestational hypertension treatment through this phase 4 clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by University of Michigan

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Expert Care in Ann Arbor

Access gestational hypertension specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related gestational hypertension treatment provided free

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Check if you qualify for this gestational hypertension clinical trial in Ann Arbor, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Gestational Hypertension Study in Ann Arbor

This trial is a pilot-scale, single institution randomized, placebo-controlled trial to assess the feasibility, acceptability, and efficacy of administering dapagliflozin for cardiovascular risk reduction in the postpartum period. The target population is patients at high risk of adverse cardiovascular outcomes within five years post-delivery. Eligible participants will be randomized to receive either: 1) dapagliflozin (10mg daily) for six months (DAPA group) or 2) an orally administered, daily placebo (Control group). The study hypothesizes: The dapagliflozin group will have higher cardiovascular risk reduction scores than the Control Group.

Sponsor: University of Michigan

Who Can Participate

Inclusion Criteria

Admitted for delivery at the University of Michigan (UM) Labor and Delivery (L\&D) unit or enrolled in the UM postpartum blood pressure monitoring program following a delivery at the UM L\&D unit
Determined to be at least 23 and 0/7 weeks of gestation based on a clinically acceptable dating method (can be a single or multifetal gestation with or without the presence of fetal anomalies) at the time of delivery
Consents to participation and must understand/read/speak English with the ability to understand and willingness to sign a written informed consent in English
Diagnosed with a hypertensive pregnancy by either of the following criteria:
Taking an antihypertensive medication for the diagnosis of chronic or essential hypertension at the time of admission
Hypertension, chronic hypertension, or essential hypertension must be present in the prospective participant's medical record
Antihypertensive" can be any medication taken for the purpose of blood pressure control per the medical record
A documented hypertensive disorder of pregnancy (gestational hypertension, preeclampsia without severe features, preeclampsia with severe features, superimposed preeclampsia, or eclampsia) prior to delivery
Eligible participants must report a planned contraceptive method as part of the consent process, to be noted on their consent document.
Has two or more blood pressures ≥160/110 Millimeters of mercury (mmHg) at least 60 minutes apart
If an admitted patient does not meet this blood pressure criterion but is otherwise eligible, participants can consent to have a BNP drawn within 12 hours of delivery as an alternative measure of cardiovascular risk (if the brain natriuretic peptide (BNP) is ≥100 Picograms per milliliter (pg/ml), participants are eligible to participate)

Exclusion Criteria

Non-English speaking
Ongoing pregnancy
Stated desire to become pregnant within 8 months post-delivery
Intention to breastfeed after enrollment
BNP ≥1000 pg/ml within 12 hours of delivery, clinical team to be notified of result
Comorbidities that may affect cardiovascular risk assessment (per protocol)
Contraindication to dapagliflozin (per protocol)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT06785116) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Gestational Hypertension Treatment Options in Ann Arbor, MI

If you're searching for gestational hypertension treatment options in Ann Arbor, MI, this clinical trial (NCT06785116) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this phase 4 clinical trial. You'll receive care from experienced gestational hypertension specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all gestational hypertension clinical trials near you to find additional studies recruiting in your area.

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