Harrison, NYNCT07223034Now EnrollingIRB Ready

Glioma Clinical Trial in Harrison, NY

Access cutting-edge glioma treatment through this clinical trial at a research site in Harrison. Study-provided care at no cost to qualified participants.

Sponsored by Memorial Sloan Kettering Cancer Center

Quick Self-Assessment

See if you qualify for this Harrison location

Preparing your pre-screening questions…

Expert Care in Harrison

Access glioma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related glioma treatment provided free

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Check if you qualify for this glioma clinical trial in Harrison, NY

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Harrison

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Harrison site if eligible
  4. 4Begin participation

About This Glioma Study in Harrison

The researchers are doing this study to find out whether the radiopharmaceutical therapy (RPT) 177Lu-PSMA-617 is a safe treatment for people with IDH wild type glioma.

Sponsor: Memorial Sloan Kettering Cancer Center

Who Can Participate

Inclusion Criteria

Confirmed histologic diagnosis of a WHO grade 2-4 glioma that is IDH1 R132H-wildtype, including the following:
Diffuse astrocytoma, IDH-wildtype (grade 2-4)
Glioblastoma, IDH-wildtype
Diffuse midline glioma, H3 K27-altered
Diffuse hemispheric glioma, H3 G34-mutant
Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype PSMA positive pathological stain (by immunohistochemistry) of baseline (pre-radiotherapy) resection or biopsy sample
Completion of standard of care therapy including surgery (for resectable tumors) and adjuvant EBRT for glioma
Patients must be on a dose of 4 mg or less of dexamethasone (or dexamethasone equivalent steroid) for 5 days prior to first planned dose of radiopharmaceutical
Serum creatinine level \< 1.5 x ULN or EGFR \> 60 mL/min
Liver laboratory values: ALT and AST ≤ 2.5 x ULN; Albumin \> 2 g/ dL; Bilirubin \< 3 X ULN
Normal organ and marrow function as defined as the following
Total white blood count \> 3.0 K/mcL
ANC ≥ 1.5 K/mcL
Platelets ≥ 100 K/mcL
Hemoglobin ≥ 9 g/dL
Adequate contraception prior to registration (see section 9.0)
Ability to understand, and willingness to sign the informed consent.

Exclusion Criteria

Patient known to harbor any other non-canonical IDH mutations (i.e., non-R132H)
Target lesion within 5 mm of either the brainstem, optic chiasm or optic nerves Receipt of bevacizumab as part of the initial treatment for glioma
Life expectancy less than 12 weeks
Nonhealing wound, ulcer or bone fracture
History of severe brain injury
Patient not eligible for sequential MRI evaluations
Patients with prior RT to \> 25% of the skeleton or prior exposure to prior Radium223, Strontium89 or Samarium153 containing compounds
Patients with a prior or concurrent malignancy whose natural history or treatment has the potential to interfere with the safety or efficacy assessment of the investigational regimen
Unable to tolerate the PSMA PET/MR or PSMA PET/CT
History of viral hepatitis or chronic liver disease with active symptoms
History of pituitary or adrenal dysfunction
Previously diagnosed active infection (e.g., human immunodeficiency virus \[HIV\] or viral hepatitis)
Any condition that in the opinion of the investigator, would preclude participation in this study
Receipt of any other investigational agents or participation in a concurrent treatment protocol
Known allergies, hypersensitivities, or intolerance to 68Ga-PSMA-11/177Lu-PSMA-617 or its inactive compounding components
Current or planned pregnancy
Refusal to comply with detailed contraception requirements

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Harrison?

Yes, this clinical trial (NCT07223034) has an active research site in Harrison, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Glioma Treatment Options in Harrison, NY

If you're searching for glioma treatment options in Harrison, NY, this clinical trial (NCT07223034) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Harrison research site is actively enrolling participants for this clinical trial. You'll receive care from experienced glioma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all glioma clinical trials near you to find additional studies recruiting in your area.

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