Is NCT06397560 recruiting in Miami, FL?

Yes, NCT06397560 is currently recruiting participants at its Miami, FL location. This glioma clinical trial is actively enrolling qualified participants.

How do I join the glioma clinical trial in Miami?

To join this clinical trial in Miami, complete the eligibility form on this page. A study coordinator will contact you to discuss next steps and determine if you qualify.

Is participation in this Miami clinical trial free?

Yes, all study-related care is provided at no cost to qualified participants. Many studies also offer compensation for time and travel expenses.

Glioma Clinical Trial in Miami, FL

About This Glioma Study in Miami

The purpose of this research study is to see if a specific type of radiation therapy, called "proton pulsed reduced dose rate" or "PRDR radiotherapy" has any benefits at dose levels and number of fractions thought to be acceptable in earlier research studies. The researchers want to find out what effects (good and bad) PRDR has on people with cancer in the brain called a "recurrent high-grade glioma" meaning that it grows fast, can spread quickly, and it has come back or gotten worse after being treated previously.

Sponsor: Baptist Health South Florida

Who Can Participate

Inclusion Criteria

Karnofsky performance status ≥ 50

Histologically-confirmed or radiographic evidence of recurrent / progressive glioma

Prior treatment with radiotherapy to a minimum dose of 45 Gy

At least 6 months or greater between completion of prior radiotherapy and enrollment in this study. If prospective participants have not passed an interval of at least 6 months, they may still be eligible if they meet one or more of the following criteria:

New areas of tumor outside the original radiotherapy fields as determined by the investigator.

Histologic confirmation of tumor through biopsy or resection AND an interval of at least 90 days between completion of radiotherapy and enrollment.

Nuclear medicine imaging, magnetic resonance (MR) spectroscopy, or MR perfusion imaging consistent with true progressive disease, rather than radiation necrosis obtained within 28 days of enrollment AND an interval of at least 90 days between completion of radiotherapy and enrollment.

Must have recovered from grade 3+ toxicities of prior therapy and there must be a minimum time of 28 days prior to enrollment from the administration of any investigational agent or prior cytotoxic therapy

Must not be pregnant (positive pregnancy test) or breastfeeding. Must agree to use of highly effective contraception during radiotherapy treatment and for an additional 6 months. Should a participant become pregnant or suspect that they are pregnant while participating in this study, they should notify the treating physician immediately. Highly effective and acceptable forms of contraception are:

Male condom plus spermicide

Cap plus spermicide

Diaphragm plus spermicide

Progesterone T

Levonorgestrel-releasing intrauterine system (e.g., Mirena®)

Hormone shot or injection

Combined pill

Patch Individuals who meet any of the following criteria will not need contraception:

Individuals assigned male at birth

Amenorrhoeic for 1 year or more following cessation of exogenous hormonal treatments

Luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels in the postmenopausal range for individuals under 50

Radiation-induced oophorectomy with last menses \> 1 year ago

Chemotherapy-induced menopause with \>1 year interval since last menses

Surgical sterilization (bilateral oophorectomy or hysterectomy)

Exclusion Criteria

Two or more courses of prior radiotherapy

Inability to undergo an MRI with contrast

Leptomeningeal evidence of recurrent disease

Multi-focal disease

Any other condition that may put a participant at higher risk, at the discretion of the investigator.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Miami?

Yes, this clinical trial (NCT06397560) has an active research site in Miami, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Glioma Treatment Options in Miami, FL

If you're searching for glioma treatment options in Miami, FL, this clinical trial (NCT06397560) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Miami research site is actively enrolling participants for this clinical trial. You'll receive care from experienced glioma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all glioma clinical trials near you to find additional studies recruiting in your area.

Glioma Clinical Trial in Miami, FL

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