Miami, FLNCT07280156Now EnrollingIRB Ready

Gout Clinical Trial in Miami, FL

Access cutting-edge gout treatment through this clinical trial at a research site in Miami. Study-provided care at no cost to qualified participants.

Sponsored by Protalix

Quick Self-Assessment

See if you qualify for this Miami location

Preparing your pre-screening questions…

Expert Care in Miami

Access gout specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related gout treatment provided free

Apply for This Miami Location

Check if you qualify for this gout clinical trial in Miami, FL

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Miami

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Miami site if eligible
  4. 4Begin participation

About This Gout Study in Miami

This is a multicenter, randomized, double-blind, placebo-controlled phase II study assessing the efficacy, safety, and dosing regimen selection of multiple IV infusions of PRX-115 over 24 weeks, with or without MTX, versus the respective placebos in adult patients with gout.

Sponsor: Protalix

Who Can Participate

Inclusion Criteria

Males or females ≥18 years of age.
Weight within the range of 50.0 - 150.0 kg.
Gout patients who failed to normalize sUA (\<7 mg/dL) with or without xanthine oxidase inhibitors or uricosuric agent or have contraindications to these drugs.
Willing to discontinue any oral ULT
Females who are sterile, postmenopausal, or non-pregnant and using birth control methods.

Exclusion Criteria

Any condition known to have arthritis as a clinical manifestation.
Positive testing for HBV,HCV, or HIV.
The patient is a pregnant or lactating female or plans to become pregnant during the study period.
Known allergy or sensitivity to the injected proteins, including pegylated products.
Prior exposure to any experimental or marketed uricase.
Patient treated with a medication known to have an influence on urate metabolism or clearance such as ULTs.
History of anaphylaxis, severe allergic reactions, or severe atopy.
G6PD deficiency or known catalase deficiency.
History of significant hematologic or autoimmune disorders within 5 years of Screening and/or patient is immunocompromised or treated with immunosuppressive medications.
Non-compensated CHF or hospitalization for CHF (Stage 3-4 NYHA Functional Class) within 3 months of the Screening Visit, uncontrolled arrhythmia, treatment for acute coronary syndrome (myocardial infarction or unstable angina), or uncontrolled BP (\>160/100 mmHg) at screening and prior to randomization at Week -4 (Visit 1).
Current liver disease, as determined by ALT or AST levels above upper limit of normal at Screening Visit.
Chronic liver disease.
Hemoglobin \<11 g/dL, neutrophil count \<1500 /µl, or platelet count \<100,000 /µl.
Known severe pulmonary fibrosis, bronchiectasis or interstitial pneumonitis.
eGFR ≤ 40 mL/min/1.73m2 tested at Screening Visit. Kidney transplant or requires dialysis.
Known intolerance and/or known contraindication to MTX treatment or MTX treatment considered inappropriate
Has uncontrolled type 2 diabetes at Screening with HbA1c ≥8.5%. Patients with type 1 diabetes will be excluded.
Has known latent autoimmune diabetes of adult.
Immunocompromised state, regardless of etiology.
History or treatment of malignancy in the last 5 years, excluding localized, nonmelanoma skin cancers (e.g. basal or squamous cell)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Miami?

Yes, this clinical trial (NCT07280156) has an active research site in Miami, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Gout Treatment Options in Miami, FL

If you're searching for gout treatment options in Miami, FL, this clinical trial (NCT07280156) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Miami research site is actively enrolling participants for this clinical trial. You'll receive care from experienced gout specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all gout clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Miami, FL