Detroit, MINCT04886726Now EnrollingIRB Ready

Graft Versus Host Disease Clinical Trial in Detroit, MI

Access cutting-edge graft versus host disease treatment through this clinical trial at a research site in Detroit. Study-provided care at no cost to qualified participants.

Sponsored by Henry Ford Health System

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Expert Care in Detroit

Access graft versus host disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related graft versus host disease treatment provided free

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Check if you qualify for this graft versus host disease clinical trial in Detroit, MI

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Detroit

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Detroit site if eligible
  4. 4Begin participation

About This Graft Versus Host Disease Study in Detroit

So this a Phase I study with primary objective to determine the feasibility and safety of combining post-transplant cyclophosphamide and urinary-derived human chorionic gonadotropin and epidermal growth factor (uhCG/EGF) as graft versus host disease prophylaxis in stem cell transplant with MMUDs Secondary objectives are to determine the incidence acute and chronic GVHD, progression-free survival , and overall survival

Sponsor: Henry Ford Health System

Who Can Participate

Inclusion Criteria

Patients with hematologic malignancy who have the indication for Allogeneic SCT and have no MRD or MUD.
Age 18-70 years old
Performance score of at least 80% by Karnofsky
Adequate kidney and liver function as demonstrated by:
Creatinine clearance should be \>60 ml/min
Total Bilirubin \<1.5, ALT/AST/Alk Phos \< 2.5 x normal. No evidence of chronic active hepatitis or cirrhosis.
Negative Beta HCG test in a woman with childbearing potential, defined as not post-menopausal for 12 months or no previous surgical sterilization. Women of childbearing potential must be willing to use an effective contraceptive measure while on study.
Patient or patient's legal representative, parent(s) or guardian able to sign informed consent.

Exclusion Criteria

Positive for HIV, HBsAg, HCV or other viral hepatitis or cirrhosis from any cause
Active or prior CNS leukemia, unless in complete remission for at least 2 months.
History of serious chronic mental disorder or drug-abuse accompanied by documented problems of compliance with therapeutic programs.
Uncontrolled infection
Donor specific antibodies
Ejection fraction \<40% or history of heart failure or cardiovascular disease
history thrombosis or current thrombosis, family history of thrombosis, severe obesity, or thrombophilia.
Previous history hormone responsive cancer
history of seizure
history of migraine or severe headache
history of asthma
history of uterine fibroid

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Detroit?

Yes, this clinical trial (NCT04886726) has an active research site in Detroit, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Graft Versus Host Disease Treatment Options in Detroit, MI

If you're searching for graft versus host disease treatment options in Detroit, MI, this clinical trial (NCT04886726) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Detroit research site is actively enrolling participants for this clinical trial. You'll receive care from experienced graft versus host disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all graft versus host disease clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Detroit, MI