Knoxville, TNNCT06183268Now EnrollingIRB Ready

Head and Neck Cancer Clinical Trial in Knoxville, TN

Access cutting-edge head and neck cancer treatment through this clinical trial at a research site in Knoxville. Study-provided care at no cost to qualified participants.

Sponsored by Covenant Health Cancer Center

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Expert Care in Knoxville

Access head and neck cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related head and neck cancer treatment provided free

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Check if you qualify for this head and neck cancer clinical trial in Knoxville, TN

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Knoxville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Knoxville site if eligible
  4. 4Begin participation

About This Head and Neck Cancer Study in Knoxville

This purpose of this study is to examine skin reactions (called radiation dermatitis) that occur during pencil beam scanning (PBS) proton therapy. The researchers will test a unique technique called "Spot Delete" to see if it can reduce skin reactions for head \& neck patients treated with PBS. The investigators will also use a special computer model to study how the energy of the proton beam (linear energy transfer) is related to these skin reactions. The study involves creating a treatment plan based on a CT scan, which helps guide the proton beam in the body.

Sponsor: Covenant Health Cancer Center

Who Can Participate

Inclusion Criteria

The patient must consent to be in the study and must have signed an approved consent form conforming to federal and institutional guidelines.
Patients must be ≥ 18 years old.
Patient must have biopsy-proven squamous cell carcinoma, originating in the oral cavity, larynx, oropharynx, nasopharynx, or hypopharynx
Carcinoma of the neck of unknown primary site origin may be included if p16 positive
Clinical stage T1-2, N0-1, N2a-N3 or T3-4, any N (AJCC, 7th ed.), including no distant metastases
Patient can have prior surgical resection of a primary cancer in the head and neck at any previous time
Previous or concurrent chemotherapy is allowed
No serious health conditions as determined by physician that would impact ability to complete treatment or impact skin in the area of treatment

Exclusion Criteria

Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields
Head and neck radiotherapy that does NOT include at least one cervical lymph node level (I, II, III, IV, or V) in the target volume.
Women who are pregnant.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Knoxville?

Yes, this clinical trial (NCT06183268) has an active research site in Knoxville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Head and Neck Cancer Treatment Options in Knoxville, TN

If you're searching for head and neck cancer treatment options in Knoxville, TN, this clinical trial (NCT06183268) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Knoxville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced head and neck cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all head and neck cancer clinical trials near you to find additional studies recruiting in your area.

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See all head and neck cancer clinical trials recruiting in Knoxville — not just this study.

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Secure · Expert Care · Knoxville, TN