NCT05700617 · University of Chicago
Cardiac Power Output in Cardiogenic Shock Patients
What this study is about
The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.
View original scientific description
The main purpose of this study is to determine whether differences in myocardial reserve predict clinical outcomes for heart failure patients.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Referred for RHC for:
- Evaluation for advanced heart failure therapies, including LVAD, OHT, temporary or long-term inotrope therapy, or counter-pulsation (temporary or long-term with NuPulse device OR
- Accurate assessment of invasive hemodynamics due to worsening clinical status, OR
- Assessment of myocardial recovery for consideration of LVAD or counter-pulsation (temporary IABP or long-term with NuPulse device) decommissioning or removal OR
- Assessment of cardiac function and valvular abnormalities prior to planned valvular surgery for MR or AI
- Estimated glomerular filtration rate (eGFR) ≥ 30 ml/min/1.73 m2
- Age ≥ 18 years-old
- Intent for admission based on RHC data
Exclusion criteria
- eGFR \< 30 ml/min/1.73 m2
- Severe, non-revascularized coronary artery disease
- Concurrent acute coronary syndrome
- Age \< 18 years-old
- History of significant ventricular arrhythmia without an ICD
Where
- Chicago, Illinois
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jul 8, 2025 · Source of record for eligibility and locations