Mesa, AZNCT05064709Now EnrollingIRB Ready

Heart Failure Clinical Trial in Mesa, AZ

Access cutting-edge heart failure treatment through this clinical trial at a research site in Mesa. Study-provided care at no cost to qualified participants.

Sponsored by Impulse Dynamics

Quick Self-Assessment

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Expert Care in Mesa

Access heart failure specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure treatment provided free

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Check if you qualify for this heart failure clinical trial in Mesa, AZ

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Mesa

    Convenient for AZ residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Mesa site if eligible
  4. 4Begin participation

About This Heart Failure Study in Mesa

The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.

Sponsor: Impulse Dynamics

Who Can Participate

Inclusion Criteria

Signed and dated informed consent form;
Male or non-pregnant female, 18 years or older;
Diagnosed with symptomatic heart failure;
LVEF ≥40 and ≤70% (as assessed by site echo);
A. Heart failure hospitalization within 12 months prior to study consent OR an urgent heart failure visit requiring IV therapy within 6 months prior to study consent OR B. If there is no heart failure hospitalization within 12 months prior to study consent OR an urgent heart failure visit requiring IV therapy within 6 months prior to study consent, an elevated BMI-adjusted natriuretic peptide value must be achieved (Refer to Table 1 in Section 9.2.6)
Subjects must meet one of the following conditions:
Have stable, scheduled oral loop diuretic treatment (not just PRN) for a minimum of 30 days before providing study consent unless there is a documented allergy or intolerance.
Eligibility for enrollment is maintained for patients on an SGLT2 inhibitor without prescribed concurrent standing loop diuretic therapy if investigators provide instructions for a flexible PRN diuretic regimen (deemed appropriate by the clinician in response to symptoms or weight gain) Note: Stable is defined as no more than a 100% increase or 50% decrease in dose within the last 30 days. A one-time hold of diuretic dosing for 24 hours during the 30-day period is allowed and not an

Exclusion Criteria

ary event. Exclusion Criteria:
Resting ventricular rate \<50 or \>110 bpm;
Resting systolic blood pressure \<100 or ≥160 mmHg;
BMI greater than 46
Any severe valvular stenotic disease or any severe valvular regurgitation;
Mechanical tricuspid valve;
Complex congenital heart disease;
Exercise tolerance limited by a condition other than heart failure that, in the opinion of the investigator, contributes significantly to the primary symptoms of shortness of breath and/or exercise intolerance;
Unable to walk at least 100 meters or walks more than 450 meters during a 6MWT;
A KCCQ CCS score higher than 85;
Hypertrophic, infiltrative/restrictive or inflammatory cardiomyopathy;
Unstable angina pectoris within 30 days prior to study consent;
Acute, decompensated heart failure requiring IV therapy or ultrafiltration within 30 days prior to consent, in the hospital or an outpatient setting;
Receiving cardiac resynchronization therapy (CRT); NOTE: Subjects with active/ongoing cardiac resynchronization therapy (CRT) implanted more than one year ago are eligible for inclusion if they are currently classified as NYHA class III or higher.
Scheduled for a cardiac surgery or a percutaneous cardiac intervention (PCI) or have undergone cardiac surgery within 90 days or a PCI procedure within 30 days prior to study consent;
Myocardial infarction within 90 days prior to study consent;
Prior heart transplant or ventricular assist device;
Planning to become pregnant during the study;
Dialysis (permanent) or GFR \<15 ml/min/1.73m2;
Participating in another investigational drug or device study that may interfere with the interpretation of study data;
Currently undergoing active chemotherapeutic and/or radiation treatment for cancer or has a history of chemotherapy during the 2-year period prior to study consent;
Expected lifespan of less than 18 months from time of study consent;
Unable to follow through study protocol for any reasons in the investigator's judgement.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Mesa?

Yes, this clinical trial (NCT05064709) has an active research site in Mesa, AZ that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure Treatment Options in Mesa, AZ

If you're searching for heart failure treatment options in Mesa, AZ, this clinical trial (NCT05064709) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Mesa research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure clinical trials near you to find additional studies recruiting in your area.

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