Baltimore, MDNCT03775577Now EnrollingIRB Ready

Heart Failure With Normal Ejection Fraction Clinical Trial in Baltimore, MD

Access cutting-edge heart failure with normal ejection fraction treatment through this clinical trial at a research site in Baltimore. Study-provided care at no cost to qualified participants.

Sponsored by Johns Hopkins University

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Expert Care in Baltimore

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure with normal ejection fraction treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Baltimore

    Convenient for MD residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Baltimore site if eligible
  4. 4Begin participation

About This Heart Failure With Normal Ejection Fraction Study in Baltimore

The investigators are studying whether metabolic abnormalities in cardiac and skeletal muscle in patients with heart failure with preserved ejection fraction (HFpEF) are associated with debilitating exercise intolerance.

Sponsor: Johns Hopkins University

Who Can Participate

Inclusion Criteria

Patients of either gender who are greater than 21 years of age (no upper age limit),
Permission of patient's clinical attending physician,
Previous clinical diagnosis of HF with current New York Heart Association (NYHA) Class II-III symptoms for at least 1 month,
Left ventricular ejection fraction (EF) \>50% by echocardiography, MRI, CT or x-ray or nuclear ventriculography within prior 12 months,
Stable medical therapy for at least 30 days (no addition or removal or major (\>100%) dose change of Renin-Angiotensin-Aldosterone System (RAAS) antagonists, beta-blockers, or calcium channel blockers for hypertension).

Exclusion Criteria

Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent,
Contraindications to MRI such as implanted metallic objects (pre-existing cardiac pacemakers, cerebral clips) or indwelling metallic projectiles,
Significant valvular abnormalities,
Pregnant women (women of childbearing potential will undergo blood or urine pregnancy testing),
History of clinical CAD or significant epicardial coronary disease (\>50% stenosis) in major coronary artery by x-ray or CT angiography unless (a) the patient underwent prior successful revascularization with percutaneous coronary angioplasty within the prior three years and (b) there are no residual lesions of \>50% on the most recent coronary angiographic study.
History of infiltrative cardiomyopathy or constrictive pericarditis,
Cor pulmonale,
Significant pulmonary disease,
Estimated glomerular filtration rate (eGFR) \<20ml/min,
Any condition other than HF which could limit the ability to perform a 6MW or cardiopulmonary exercise test (CPET) test (e.g., critical peripheral vascular disease, significant orthopedic or neurological conditions),
Any diseases other than HF which are likely to significantly alter the patient's global perception of status or quality of life over a period of 6 months.
Significant peripheral vascular disease

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Baltimore?

Yes, this clinical trial (NCT03775577) has an active research site in Baltimore, MD that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure With Normal Ejection Fraction Treatment Options in Baltimore, MD

If you're searching for heart failure with normal ejection fraction treatment options in Baltimore, MD, this clinical trial (NCT03775577) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Baltimore research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure with normal ejection fraction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure with normal ejection fraction clinical trials near you to find additional studies recruiting in your area.

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