Rochester, MNNCT07083011Now EnrollingIRB Ready

Heart Failure With Preserved Ejection Fraction Clinical Trial in Rochester, MN

Access cutting-edge heart failure with preserved ejection fraction treatment through this clinical trial at a research site in Rochester. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Rochester

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related heart failure with preserved ejection fraction treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Rochester

    Convenient for MN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Rochester site if eligible
  4. 4Begin participation

About This Heart Failure With Preserved Ejection Fraction Study in Rochester

The purpose of this study is to assess the performance of 68Ga- FAPI PET in heart failure with preserved ejection fraction (HFpEF)

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Patients aged ≥ 30 years old with exertional dyspnea (NYHA II and III) and LVEF ≥50%
New diagnosis of HFpEF based on RHC at baseline (elevated PCWP at rest and/or during exercise) HFpEF Group

Exclusion Criteria

Primary cardiomyopathy or pericardial disease or ≥ moderate valvular disease
Dyspnea due to lung disease or CAD
Severe anemia, liver, or renal disease
Active cancer
Systemic active inflammatory or autoimmune disease (e.g. rheumatoid arthritis, SLE, etc.)
Recent hospitalization (\< 30 days) or coronary revascularization (\< 90 days)
Patients already taking SGLT2i and/or GLP-1A
Pregnant or breastfeeding
Inability to tolerate supine position for the PET/CT or CMR scans.
Contraindications for safe CMR scanning (e.g., uncontrolled claustrophobia, cochlear implant, implanted neural stimulator)
Known gadolinium allergy
Presence of implantable cardiac pacemaker or defibrillator or mechanical valve. Cardiac Sarcoid Group Inclusion:
Ambulatory patients aged ≥ 18 years old
New referrals to the Sarcoid Clinic with a confirmed but untreated diagnosis of definite or probable CS based on 2014 HRS consensus (see Table 2)
With a positive cardiac 18F-FDG PET scan within 30 days. Cardiac Sarcoid Group Exclusion:
Already on immunosuppressive therapy
Pregnant or breastfeeding
Severe liver or renal disease (estimated GFR \< 30 or dialysis-dependent)
Recent coronary revascularization (\< 90 days)
Active cancer
Known gadolinium allergy
Inability to tolerate supine position for the PET/CT or CMR scans.
Contraindications for safe CMR scanning (e.g., uncontrolled claustrophobia, cochlear implant, implanted neural stimulator)
Presence of implantable cardiac pacemaker or defibrillator or mechanical valve. Healthy Controls Group Inclusion:
Adults ≥ 30 years old
No major chronic disease (cardiopulmonary, inflammatory, autoimmune, cancer, renal or liver impairment, etc.)
No intake of relevant medication, defined as regular intake of at least one of the following: anticoagulants, antiplatelets, antihypertensive / diuretics, antidiabetics, antiarrhythmic, immunosuppressants, chemotherapy, antibiotics/antivirals/antifungals Healthy Controls Group Exclusion:
Pregnant or breastfeeding
Known gadolinium allergy
Inability to tolerate supine position for the PET/CT or CMR scans.
Contraindications for safe CMR scanning (e.g., uncontrolled claustrophobia, cochlear implant, implanted neural stimulator)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Rochester?

Yes, this clinical trial (NCT07083011) has an active research site in Rochester, MN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Heart Failure With Preserved Ejection Fraction Treatment Options in Rochester, MN

If you're searching for heart failure with preserved ejection fraction treatment options in Rochester, MN, this clinical trial (NCT07083011) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Rochester research site is actively enrolling participants for this clinical trial. You'll receive care from experienced heart failure with preserved ejection fraction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all heart failure with preserved ejection fraction clinical trials near you to find additional studies recruiting in your area.

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