Houston, TXNCT02464696Now EnrollingIRB Ready

Hematopoietic and Lymphoid Cell Neoplasm Clinical Trial in Houston, TX

Access cutting-edge hematopoietic and lymphoid cell neoplasm treatment through this clinical trial at a research site in Houston. Study-provided care at no cost to qualified participants.

Sponsored by M.D. Anderson Cancer Center

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Expert Care in Houston

Access hematopoietic and lymphoid cell neoplasm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hematopoietic and lymphoid cell neoplasm treatment provided free

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Check if you qualify for this hematopoietic and lymphoid cell neoplasm clinical trial in Houston, TX

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Why Participate?

  • No-Cost Study Care

  • Local to Houston

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Houston site if eligible
  4. 4Begin participation

About This Hematopoietic and Lymphoid Cell Neoplasm Study in Houston

This randomized clinical trial studies how well non-invasive ventilation works in reducing the need for intubation, or placement of a tube in the windpipe, in patients with cancer and respiratory failure. Respiratory failure is a condition in which not enough oxygen passes from the lungs to the blood, and is a common cause of admission to the emergency room in patients with hematological and solid tumor patients. Non-invasive positive pressure ventilation (NIPPV) is a method of delivering oxygen using a mask. It is not yet known whether NIPPV is better at improving the amount of oxygen in the blood, reducing shortness of breath, and the need for intubation than standard high flow oxygen (a tube with 2 prongs placed in the nostrils) in patients with cancer and respiratory failure.

Sponsor: M.D. Anderson Cancer Center

Who Can Participate

Inclusion Criteria

Partial pressure of arterial oxygen (PaO2):fraction of inspired oxygen (FiO2) ratio =\< 300 mmHg OR a peripheral capillary oxygen saturation (SaO2):FiO2 =\< 357
Have a diagnosed malignancy
Chest radiograph or computed tomography (CT) scan within =\< 3 months prior to study enrollment rules out primary or metastatic malignancy in the lungs or pleural space as a significant cause of respiratory insufficiency
Probability of survival is at least 6 months

Exclusion Criteria

Presence of do not resuscitate (DNR)/do not intubate (DNI) orders at study entry
Clinical evidence of left heart failure as the main etiology for respiratory compromise
Evidence of active intrathoracic malignancy (primary or metastatic) in the lungs or pleural space that is a significant cause of respiratory insufficiency
Patients with acute chronic obstructive disease exacerbation as the primary etiology for respiratory failure
Evidence of accessory respiratory muscle use with breathing
Shock (need for vasopressor therapy or mean arterial pressure \[MAP\] \< 60 despite fluid administration)
Oliguric acute renal failure (urine output \< 500 ml/day) unless already on hemodialysis
Patient already on NIPPV at the time of screening
pH \< 7.30 or partial pressure of carbon dioxide (pCO2) \> 50 (if available)
Fixed upper airway obstruction
Airway or facial trauma that would hinder the use of a NIPPV mask
Uncontrolled tachy or bradyarrhythmia or active myocardial ischemia defined as either: atrial fibrillation with rapid ventricular response (heart rate \[HR\] \> 120 beats per minute \[bpm\]), ventricular tachycardia or nonsustained ventricular tachycardia (any rate), supraventricular tachycardia (any rate), third degree heart block (any rate), heart rate less than 40 beats per minute (regardless of the rhythm)
Active myocardial ischemia defined as a clinical presentation at the time of screening consistent with acute coronary syndrome which includes unstable angina and electrocardiogram (EKG) changes suggestive of an either an acute ST elevation myocardial infarction (new ST elevations or new left bundle branch block) or acute non-ST elevation myocardial infarction (new ST depressions, new T wave inversions)
Glasgow Coma Scale (GCS) \< 8 or inadequate airway protective reflexes
Undrained pneumothorax/pneumomediastinum
Copious secretions (\> 20 cc's of sputum production per hour or significant hemoptysis defined as \> 100 cc's of hemoptysis in a 24 hour period
Risk for gastric aspiration (ie; ileus, esophageal or bowel obstruction, active vomiting)
Recent esophageal, gastric or bowel surgery (within 3 weeks of study enrollment)
Inability to cooperate with NIPPV
Refusal to receive NIPPV
Respiratory arrest

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Houston?

Yes, this clinical trial (NCT02464696) has an active research site in Houston, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hematopoietic and Lymphoid Cell Neoplasm Treatment Options in Houston, TX

If you're searching for hematopoietic and lymphoid cell neoplasm treatment options in Houston, TX, this clinical trial (NCT02464696) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Houston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hematopoietic and lymphoid cell neoplasm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hematopoietic and lymphoid cell neoplasm clinical trials near you to find additional studies recruiting in your area.

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