Dallas, TXNCT07223242Now EnrollingIRB Ready

HFpEF - Heart Failure With Preserved Ejection Fraction Clinical Trial in Dallas, TX

Access cutting-edge hfpef - heart failure with preserved ejection fraction treatment through this clinical trial at a research site in Dallas. Study-provided care at no cost to qualified participants.

Sponsored by University of Texas Southwestern Medical Center

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This study follows strict safety protocols and ethical guidelines

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Why Participate?

  • No-Cost Study Care

  • Local to Dallas

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Dallas site if eligible
  4. 4Begin participation

About This HFpEF - Heart Failure With Preserved Ejection Fraction Study in Dallas

Heart failure with preserved ejection fraction (HFpEF) is associated with a high morbidity and mortality burden. There are limited pharmacological options available for the treatment of HFpEF. Exercise intolerance (EI) is the cardinal symptom of HFpEF, which manifests as dyspnea and fatigue. EI leads to functional deconditioning and reduced quality of life (QOL), both of which elevate risk of death and hospitalization in patients with HFpEF. Supervised exercised training is associated with improvements in exercise capacity and QOL in adults with HFpEF. However, supervised exercise has not been widely utilized for the treatment of HFpEF due to logistical and fiscal barriers. This study will investigate the effects of a remote exercise training intervention on exercise capacity and skeletal muscle composition in patients with HFpEF, or those at risk for it. In addition, it will compare four different lifestyle interventions for their effects on exercise capacity.

Sponsor: University of Texas Southwestern Medical Center

Who Can Participate

Inclusion Criteria

Age\>= 18 yrs
LVEF (Left Ventricular Ejection Fraction) \>= 50%
History of HFpEF or at risk of HFpEF
HFpEF diagnosis based on:- -HF hospitalization within 12 months-
NT-proBNP \>360 pg/mL
Risk of HFpEF based on:-
\>2 risk factors (h/o diabetes, hypertension, obesity, physical inactivity by self-report)
SPPB \< 10 or VO2\<60th percentile
BMI \>=28 (for randomization in phase II)
Able to use cell phone and mobile application

Exclusion Criteria

Hospitalization 1 month prior to baseline visit
History of recurrent falls
eGFR (Estimated Glomerular Filtration Rate) \<20ml/min/1.73m
Active changes in HF therapies over 2 weeks prior to baseline visit
Inability participate in exercise training therapy
Inability to perform CPET (Cardiopulmonary Exercise Testing) testing
Severe left side valvular heart disease
End stage pulmonary disease, requiring continuous supplemental oxygen
Major surgery within 3 months of screening or major elective surgery during the duration of the study.
Unstable weight defined by \>5% change in body weight in last 30 days before first study visit.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Dallas?

Yes, this clinical trial (NCT07223242) has an active research site in Dallas, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

HFpEF - Heart Failure With Preserved Ejection Fraction Treatment Options in Dallas, TX

If you're searching for hfpef - heart failure with preserved ejection fraction treatment options in Dallas, TX, this clinical trial (NCT07223242) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Dallas research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hfpef - heart failure with preserved ejection fraction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hfpef - heart failure with preserved ejection fraction clinical trials near you to find additional studies recruiting in your area.

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