Boston, MANCT07077395Now EnrollingIRB Ready

Hot Flashes Clinical Trial in Boston, MA

Access cutting-edge hot flashes treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Massachusetts General Hospital

Quick Self-Assessment

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Expert Care in Boston

Access hot flashes specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related hot flashes treatment provided free

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Check if you qualify for this hot flashes clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Hot Flashes Study in Boston

The goal of this clinical trial is to learn if drug fezolinetant improves blood vessel health in women with moderate to severe hot flashes. The main questions it aims to answer are: Does drug fezolinetant improve blood vessel health?

Sponsor: Massachusetts General Hospital

Who Can Participate

Inclusion Criteria

Age 40-65 years
Peri- and post-menopausal women (STRAW -1 to +1)
Moderate or high vasmotor symptom burden
Cardiometabolic disease (as evidenced by ≥ 2 of the following):
Obesity (body mass index ≥ 30 kg/m2)
Elevated waist circumference (≥ 88 cm)
Elevated triglycerides (≥ 150 mg/dL or drug treatment)
Reduced HDL-cholesterol (\<50 mg/dL or drug treatment)
Elevated blood pressure (≥ 130 mmHg systolic blood pressure or ≥ 85 mmHg diastolic blood pressure, or drug treatment)
Elevated fasting glucose (≥ 100 mg/dL or drug treatment)

Exclusion Criteria

Inability to provide informed consent or comply with study protocol
Major comorbidities: cancer, end-stage renal (eGFR \<45 mL/min/1.73 m2), liver or lung disease
Concomitant use of strong or moderate cytochrome P450 1A2 inhibitors
Elevated liver function tests (ALT, AST, and/or total bilirubin ≥2x ULN)
Undiagnosed uterine bleeding over past 6 months

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT07077395) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Hot Flashes Treatment Options in Boston, MA

If you're searching for hot flashes treatment options in Boston, MA, this clinical trial (NCT07077395) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced hot flashes specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all hot flashes clinical trials near you to find additional studies recruiting in your area.

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