Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Menopause Clinical Trials
Menopause clinical trials are recruiting across 41 cities. Here are the cities with the most active studies:
Menopause Trial Phases
36 research organizations are sponsoring menopause trials.
About Menopause
Menopause marks the end of menstrual cycles, typically occurring in the late 40s to early 50s, and brings symptoms like hot flashes, mood changes, and bone loss. The menopausal transition can last several years. Management includes hormone replacement therapy, non-hormonal medications, and lifestyle changes.
Clinical trials are advancing new treatments for menopause. Currently, 49 studies are recruiting a combined 5,169 participants across the United States. Research is being conducted by 36 organizations including Brigham and Women's Hospital, University of Arizona, Corium Innovations, Inc. and 33 others.
2026 Menopause Research Landscape
As of October 2026, the menopause clinical trial landscape includes 49 actively recruiting studies across 41 cities in the United States. These studies are collectively seeking 5,169 participants, with an average enrollment target of 105 per study.
The research spans multiple phases of development: 30 studies are in NA, 6 studies are in PHASE4, 4 studies are in PHASE2, 3 studies are in PHASE1, 2 studies are in EARLY_PHASE1, 1 study is in PHASE3. The presence of Phase 3 trials indicates that some menopause treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 36 different organizations, including Brigham and Women's Hospital, University of Arizona, Corium Innovations, Inc., Bonafide Health, University of Colorado, Denver, and 31 others. The large number of sponsors reflects significant research interest and investment in menopause treatment advancement.
Geographically, menopause trials are most concentrated in Boston, Massachusetts (5 trials); Aurora, Colorado (4 trials); Rochester, Minnesota (4 trials); University Park, Pennsylvania (2 trials); Ann Arbor, Michigan (2 trials) and 7 other cities.
Featured Menopause Studies
Highlighted recruiting studies for menopause, selected by enrollment size and research scope.
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms
The goal of this clinical trial is to learn how three current insomnia therapies (trazodone, daridorexant, cognitive behavioral therapy for insomnia) compare with each other in peri- and post-menopausal women. It will also learn about the safety of the treatments. The main questions it aims to answer are: Which commonly used insomnia therapies are most effective and safe for improving insomnia sy...
VEDA Study (DHEA vs Estradiol)
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause. These symptoms may include vaginal dryness, discomfort, painful intercourse, or urinary problems and can affect quality of life and sexual health. Women who choose to participate will be randomly assigned to use one of the two trea...
A Study to Assess the Skin Irritation and Sensitization of Estradiol/Levonorgestrel TDS in Healthy Postmenopausal Subjects
The two products used in this study are transdermal patches that contain selegiline. The test drug is the Estradiol/Levonorgestrel Transdermal Delivery System (TDS). The comparator drug is the Climara Pro® TDS. The purpose of this research study is to compare how the skin tolerates the test TDS and the comparator TDS. The study will evaluate and compare skin irritation and possible allergic-type ...
Frequently Asked Questions About Menopause Clinical Trials
Are there menopause clinical trials near me?
Yes, there are 49 menopause clinical trials currently recruiting across 41+ cities in the United States, including Boston, Massachusetts; Aurora, Colorado; Rochester, Minnesota. Browse the studies above to find one at a location convenient for you.
How do I join a menopause clinical trial?
To join a menopause clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are menopause clinical trials free?
Yes, participation in menopause clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of menopause treatments are being studied?
Current menopause clinical trials are testing a range of approaches across NA (30 studies), PHASE4 (6 studies), PHASE2 (4 studies), PHASE1 (3 studies), EARLY_PHASE1 (2 studies), PHASE3 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 36 research organizations.
Is it safe to participate in menopause clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated October 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated October 15, 2026 · Data from ClinicalTrials.gov