Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Menopause Clinical Trials
Menopause clinical trials are recruiting across 33 cities. Here are the cities with the most active studies:
Menopause Trial Phases
30 research organizations are sponsoring menopause trials.
About Menopause
Menopause marks the end of menstrual cycles, typically occurring in the late 40s to early 50s, and brings symptoms like hot flashes, mood changes, and bone loss. The menopausal transition can last several years. Management includes hormone replacement therapy, non-hormonal medications, and lifestyle changes.
Clinical trials are advancing new treatments for menopause. Currently, 38 studies are recruiting a combined 3,966 participants across the United States. Research is being conducted by 30 organizations including Brigham and Women's Hospital, Bonafide Health, University of Colorado, Denver and 27 others.
2026 Menopause Research Landscape
As of July 2026, the menopause clinical trial landscape includes 38 actively recruiting studies across 33 cities in the United States. These studies are collectively seeking 3,966 participants, with an average enrollment target of 104 per study.
The research spans multiple phases of development: 24 studies are in NA, 4 studies are in PHASE4, 4 studies are in PHASE2, 2 studies are in EARLY_PHASE1, 1 study is in PHASE3, 1 study is in PHASE1. The presence of Phase 3 trials indicates that some menopause treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 30 different organizations, including Brigham and Women's Hospital, Bonafide Health, University of Colorado, Denver, Chronic Conditions Research Fund, Emory University, and 25 others. The large number of sponsors reflects significant research interest and investment in menopause treatment advancement.
Geographically, menopause trials are most concentrated in Boston, Massachusetts (5 trials); Rochester, Minnesota (3 trials); Aurora, Colorado (2 trials); University Park, Pennsylvania (2 trials); Minneapolis, Minnesota (2 trials) and 7 other cities.
Featured Menopause Studies
Highlighted recruiting studies for menopause, selected by enrollment size and research scope.
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms
The goal of this clinical trial is to learn how three current insomnia therapies (trazodone, daridorexant, cognitive behavioral therapy for insomnia) compare with each other in peri- and post-menopausal women. It will also learn about the safety of the treatments. The main questions it aims to answer are: Which commonly used insomnia therapies are most effective and safe for improving insomnia sy...
JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women
The goal of this interventional study is to evaluate whether the study product can help improve quality of life and reduce common menopause symptoms-such as joint discomfort, hot flashes and night sweats-in women aged 50-70. The primary research question is whether taking the study product daily for 12 weeks can reduce the severity and frequency of menopause-related symptoms.
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
What if midlife women, who are inherently at an increased risk for future cardiometabolic disease due to transitioning into menopause, had access to a suite of evidence-based health interventions? Could these interventions reduce menopause-related inflammation, restore a healthier cardiometabolic profile, reverse epigenetic aging, and reduce bothersome menopausal symptoms? The ultimate goal of thi...
Frequently Asked Questions About Menopause Clinical Trials
Are there menopause clinical trials near me?
Yes, there are 38 menopause clinical trials currently recruiting across 33+ cities in the United States, including Boston, Massachusetts; Rochester, Minnesota; Aurora, Colorado. Browse the studies above to find one at a location convenient for you.
How do I join a menopause clinical trial?
To join a menopause clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are menopause clinical trials free?
Yes, participation in menopause clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of menopause treatments are being studied?
Current menopause clinical trials are testing a range of approaches across NA (24 studies), PHASE4 (4 studies), PHASE2 (4 studies), EARLY_PHASE1 (2 studies), PHASE3 (1 study), PHASE1 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 30 research organizations.
Is it safe to participate in menopause clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov