Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Premature Birth Clinical Trials
Premature Birth clinical trials are recruiting across 72 cities. Here are the cities with the most active studies:
Premature Birth Trial Phases
36 research organizations are sponsoring premature birth trials.
About Premature Birth
Premature birth is delivery before 37 weeks of pregnancy and is the leading cause of infant death and disability worldwide. Complications can affect the brain, lungs, and other developing organs. Prevention strategies include progesterone therapy, cervical cerclage, and prenatal care.
Clinical trials are advancing new treatments for premature birth. Currently, 43 studies are recruiting a combined 48,706 participants across the United States. Research is being conducted by 36 organizations including Children's Hospital of Philadelphia, The George Washington University Biostatistics Center, Mayo Clinic and 33 others.
2026 Premature Birth Research Landscape
As of July 2026, the premature birth clinical trial landscape includes 43 actively recruiting studies across 72 cities in the United States. These studies are collectively seeking 48,706 participants, with an average enrollment target of 1,133 per study.
The research spans multiple phases of development: 26 studies are in NA, 3 studies are in PHASE3, 3 studies are in PHASE2, 2 studies are in PHASE1. The presence of Phase 3 trials indicates that some premature birth treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 36 different organizations, including Children's Hospital of Philadelphia, The George Washington University Biostatistics Center, Mayo Clinic, HELP for NOWS Consortium, Michelle Baczynski, and 31 others. The large number of sponsors reflects significant research interest and investment in premature birth treatment advancement.
Geographically, premature birth trials are most concentrated in Birmingham, Alabama (5 trials); Boston, Massachusetts (5 trials); Philadelphia, Pennsylvania (4 trials); Little Rock, Arkansas (3 trials); San Diego, California (3 trials) and 7 other cities.
Featured Premature Birth Studies
Highlighted recruiting studies for premature birth, selected by enrollment size and research scope.
Supraglottic Airway for Resuscitation Trial
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on implementation outcomes.
Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial
This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg aspirin or 81 mg aspirin daily. The study drug will be initiated between 10 and 15 weeks gestation and continued through 36 weeks, 6 days gestation. The primary endpoint is recurrent preterm delivery o...
The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals
The purpose of this study is to evaluate the impact of real-time audio-video telemedicine consults with a neonatologist (termed teleneonatology) on the early health outcomes of at-risk neonates delivered in community hospitals.
Frequently Asked Questions About Premature Birth Clinical Trials
Are there premature birth clinical trials near me?
Yes, there are 43 premature birth clinical trials currently recruiting across 72+ cities in the United States, including Birmingham, Alabama; Boston, Massachusetts; Philadelphia, Pennsylvania. Browse the studies above to find one at a location convenient for you.
How do I join a premature birth clinical trial?
To join a premature birth clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are premature birth clinical trials free?
Yes, participation in premature birth clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of premature birth treatments are being studied?
Current premature birth clinical trials are testing a range of approaches across NA (26 studies), PHASE3 (3 studies), PHASE2 (3 studies), PHASE1 (2 studies). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 36 research organizations.
Is it safe to participate in premature birth clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov