A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatm...
Prescription of Letrozole for Uterine Myoma
The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and qualit...
FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea
The objective of this study is to determine the effect of low caffeine green tea extract containing 45% epigallocatechin gallate (EGCG) on fibroids and subsequent pregnancy and live births in women se...
Top Cities for Uterine Fibroids Clinical Trials
Uterine Fibroids clinical trials are recruiting across 15 cities. Here are the cities with the most active studies:
About Uterine Fibroids
Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. They can cause heavy bleeding, pelvic pain, and reproductive issues. Treatment options include medications, focused ultrasound, uterine artery embolization, and surgery.
Clinical trials are advancing new treatments for uterine fibroids. Currently, 3 studies are recruiting a combined 1,190 participants across the United States. Research is being conducted by 3 organizations including Sumitomo Pharma Switzerland GmbH, University of California, San Francisco, Yale University.
2026 Uterine Fibroids Research Landscape
As of March 2026, the uterine fibroids clinical trial landscape includes 3 actively recruiting studies across 15 cities in the United States. These studies are collectively seeking 1,190 participants, with an average enrollment target of 397 per study.
Research is being led by 3 different organizations, including Sumitomo Pharma Switzerland GmbH, University of California, San Francisco, Yale University.
Geographically, uterine fibroids trials are most concentrated in Chicago, Illinois (2 trials); Mobile, Alabama (1 trial); Chandler, Arizona (1 trial); Mesa, Arizona (1 trial); Peoria, Arizona (1 trial) and 7 other cities.
Featured Uterine Fibroids Studies
Highlighted recruiting studies for uterine fibroids, selected by enrollment size and research scope.
A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis
The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatment follow-up in premenopausal women with heavy menstrual bleeding associated with uterine leiomyomas (fibroids) or with moderate-to-severe pain associated with endometriosis.
Prescription of Letrozole for Uterine Myoma
The PLUM Study is a randomized, double-blinded, 2-arm, parallel-group, placebo-controlled trial is designed to compare the efficacy of letrozole versus placebo on leiomyoma-related symptoms and quality of life as well as leiomyoma and uterine size.
FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea
The objective of this study is to determine the effect of low caffeine green tea extract containing 45% epigallocatechin gallate (EGCG) on fibroids and subsequent pregnancy and live births in women seeking fertility treatment. The population will consist of 50 women desirous of conceiving, ages ≥18 to ≤40 years (at time of consent), and known to have class 2-6 fibroids, according to the FIGO stag...
Frequently Asked Questions About Uterine Fibroids Clinical Trials
Are there uterine fibroids clinical trials near me?
Yes, there are 3 uterine fibroids clinical trials currently recruiting across 15+ cities in the United States, including Chicago, Illinois; Mobile, Alabama; Chandler, Arizona. Browse the studies above to find one at a location convenient for you.
How do I join a uterine fibroids clinical trial?
To join a uterine fibroids clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are uterine fibroids clinical trials free?
Yes, participation in uterine fibroids clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of uterine fibroids treatments are being studied?
Current uterine fibroids clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in uterine fibroids clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov