Orlando, FLNCT06448546Now EnrollingIRB Ready

Huntington Disease Clinical Trial in Orlando, FL

Access cutting-edge huntington disease treatment through this clinical trial at a research site in Orlando. Study-provided care at no cost to qualified participants.

Sponsored by University of Central Florida

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Expert Care in Orlando

Access huntington disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related huntington disease treatment provided free

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Check if you qualify for this huntington disease clinical trial in Orlando, FL

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Why Participate?

  • No-Cost Study Care

  • Local to Orlando

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orlando site if eligible
  4. 4Begin participation

About This Huntington Disease Study in Orlando

The purpose of this study is to find out if there is a connection between the naturally occurring bacteria in our bodies and the progression of Huntington disease. The investigators are trying to determine if patients who are diagnosed with adult-onset HD and who exhibit a rapid rate of disease progression have unique populations of bacteria in their gut as compared to patients with slower progression.

Sponsor: University of Central Florida

Who Can Participate

Inclusion Criteria

18 years or older
Provide informed consent
Able to read and speak English
Agree to comply with study procedures
CAG repeat length ≤ 26.
BMI 18.5-24.9
BMI \< 18.5 (underweight) or significant, involuntary weight loss within the past 12 months.
CAG repeat length 40 - 59.
Documentation of the Clinical Diagnosis of HD with a high level of certainty (\>99% confidence) using the validated Unified Huntington's Disease Rating Scale (UHDRS).
Stage I-III on the Functional Assessment component of the UHDRS
BMI \> 25.0 (overweight - obesity) or BMI ≤ 25.0 with significant, unexplained weight gain within the past 12 months
CAG repeat length 40 - 59.
Documentation of the Clinical Diagnosis of HD with a high level of certainty (\>99% confidence) using the validated UHDRS.
Stage I-III on the Functional Assessment component of the UHDRS *

Exclusion Criteria

CAG repeat length ≥ 60 to exclude participants with juvenile onset HD.
CAG repeat length 36 - 39 to exclude participants with reduced penetrance. As this is a pilot study, we are primarily interested in participants with typical HD characteristics.
UHDRS Functional Capacity stage ≥ 4 to exclude late-stage HD patients who may be institutionalized and receive nutrition through a feeding tube.
Use of any of the following drugs within the last 6 months:
System antibiotics, antifungals, antivirals, or anti-parasitics (intravenous, intramuscular, or oral)
Corticosteroids (intravenous, intramuscular, oral, nasal, or inhaled)
Methotrexate, immunosuppressive cytotoxic agents, or chemotherapy
Commercial probiotics ≥ 100 million CFU (fermented foods, yogurts, and other homeopathic probiotics and prebiotics do not apply)
Use of topical antibiotics or topical steroids within the last 7 days
History of active, uncontrolled gastrointestinal disorders or diseases, including:
Inflammatory bowel disease
Ulcerative colitis
Crohn's disease
Irritable bowel syndrome
Infectious gastroenteritis, colitis, or gastritis
Clostridium difficile or Helicobacter pylori infection
Persistent or chronic constipation or diarrhea
Acute illness with or without fever at time of sample collection
Positive for HIV, hepatitis B, or hepatitis C
Confirmed or suspected immunodeficient condition/state
Major surgery of the GI tract, excluding cholecystectomy and appendectomy
Unstable dietary history within the past month, such as elimination or significant increase of a major food group in the diet
Recent history of chronic, excessive alcohol consumption
Travel outside of the United States within the last 3 months

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orlando?

Yes, this clinical trial (NCT06448546) has an active research site in Orlando, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Huntington Disease Treatment Options in Orlando, FL

If you're searching for huntington disease treatment options in Orlando, FL, this clinical trial (NCT06448546) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orlando research site is actively enrolling participants for this clinical trial. You'll receive care from experienced huntington disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all huntington disease clinical trials near you to find additional studies recruiting in your area.

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