Orlando, FLNCT06082713Now EnrollingIRB Ready

Huntington Disease Clinical Trial in Orlando, FL

Access cutting-edge huntington disease treatment through this clinical trial at a research site in Orlando. Study-provided care at no cost to qualified participants.

Sponsored by University of Central Florida

Quick Self-Assessment

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Expert Care in Orlando

Access huntington disease specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related huntington disease treatment provided free

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Check if you qualify for this huntington disease clinical trial in Orlando, FL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Orlando

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Orlando site if eligible
  4. 4Begin participation

About This Huntington Disease Study in Orlando

The primary objective of this study is to discover blood-based biomarker of brain Huntingtin (HTT) protein using extracellular vesicles to be used in evaluating target engagement in HTT lowering clinical trials. Secondary objectives of this study include developing more accurate biomarkers of Huntington disease (HD) progression or conversion and to develop standard practices for extracellular vesicle biomarker discovery research. The investigators hypothesize that brain-derived extracellular vesicles (EVs) isolated from human biofluids contain biological cargo specific to their tissue of origin that could allow their use as brain biomarkers for HD. EVs are lipid bilayer-delimited particles that are naturally released from cells in the brain. The investigators will investigate if EVs contents reflect the pathological alterations occurring with disease progression when compared with EVs isolated from biofluids of healthy non-HD persons.

Sponsor: University of Central Florida

Who Can Participate

Inclusion Criteria

18 - 75 years of age
can provide informed consent
able to read and speak English
agree to comply with study procedures (including overnight fasting, blood collection and lumbar puncture); and
has been diagnosed with HD (HD Carriers) or not been diagnosed with HD (Non-HD Carriers).

Exclusion Criteria

younger than 18 or older than 75 years old
known to carry an intermediate CAG repeat between 27 and 39 or a larger expansion of 60 or more CAG repeats
receiving nutrition through a tube
participated in a clinical drug trial within 30 days
use prescribed or non-prescribed medications that are not compatible with collection of the study samples (those that may cause excessive bleeding or prevent clotting)
positive for HIV, hepatitis B or C
have a confirmed or suspected immunodeficient condition/state
significant medical, psychiatric, or neurological morbidity is observed by the clinic physician on the day of sample collection that might impair completion of the study procedures
have needle phobia, frequent headache, significant lower spinal deformity or major surgery
received antiplatelet or anticoagulant therapy within 14 days prior to sample collection (including but not limited to: aspirin, clopidogrel, dipyridamole, warfarin, dabigatran, rivaroxaban and apixaban)
have a blood clotting or bruising disorder
do not comply with or are unwilling to undertake any of the study procedures

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Orlando?

Yes, this clinical trial (NCT06082713) has an active research site in Orlando, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Huntington Disease Treatment Options in Orlando, FL

If you're searching for huntington disease treatment options in Orlando, FL, this clinical trial (NCT06082713) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Orlando research site is actively enrolling participants for this clinical trial. You'll receive care from experienced huntington disease specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all huntington disease clinical trials near you to find additional studies recruiting in your area.

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See all huntingtons disease clinical trials recruiting in Orlando — not just this study.

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Secure · Expert Care · Orlando, FL