Ann Arbor, MINCT03687814Now EnrollingIRB Ready

Irritable Bowel Syndrome Characterized by Constipation Clinical Trial in Ann Arbor, MI

Access cutting-edge irritable bowel syndrome characterized by constipation treatment through this clinical trial at a research site in Ann Arbor. Study-provided care at no cost to qualified participants.

Sponsored by University of Michigan

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related irritable bowel syndrome characterized by constipation treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Ann Arbor

    Convenient for MI residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Ann Arbor site if eligible
  4. 4Begin participation

About This Irritable Bowel Syndrome Characterized by Constipation Study in Ann Arbor

Consecutive patients with Irritable Bowel Syndrome with Constipation (IBS-C) will be recruited from the outpatient clinics of the University of Michigan Health System. Eligible patients will be asked to participate in a study that will test the efficacy the PEG 3350 + a diet low in fermentable oligo, di, monosaccharides, and polyols (FODMAP) vs. PEG 3350 plus sham diet. Blinding dietary advice trials is challenging and therefore the sham diet was based on the criteria set forth by Staudacher et al. which emphasizes that the diet must give the impression that is the true intervention diet with similar restrictions, modifications, and time intensity without impacting the intake of essential nutrients, fiber, and FODMAPs. An example of the sham diet's carbohydrates includes: apples, bananas, and pears, and wheat. Oranges, raspberries, strawberries and rice would not be allowed. Additionally, the physicians analyzing the data will be blinded as to which group the patients were randomized.

Sponsor: University of Michigan

Who Can Participate

Inclusion Criteria

1\. Subjects aged 18 and older meeting the Rome IV criteria for IBS-C\*: • Recurrent abdominal pain, on average, at least 1 day/week in the last 3 months, associated with two or more of the following:
related to defecation
associated with a change in the frequency of stool (reduction of stools)
associated with a change in the form of stool (hard or lumpy stools) AND \>25% hard stools and \<25% loose stools \
Criteria fulfilled for the last 3 months

Exclusion Criteria

any other IBS subtype other than IBS-C
\>3 spontaneous bowel movements during the last 7 days of run-in
Have cognitive dysfunction or unable to understand or provide written informed consent
Pregnancy (evaluated by self-report)
Comorbid medical problems that may affect gastrointestinal transit or motility:
Inflammatory bowel disease
Extra-intestinal disease known to affect the gastrointestinal system (i.e., scleroderma, unstable thyroid disease, etc.)
Severe renal or hepatic disease
Previous abdominal surgery other than appendectomy, cholecystectomy, and gynecologic/urologic surgery if performed more than six months prior to enrollment
Previous treatment with the low FODMAP diet under a dietician guidance
Concurrent medications not permitted including probiotics, antibiotics, prescription or over-the-counter medication for IBS, and narcotics
New antidepressant use (less than 3 months on stable dose)
Active participation in another form of dietary therapy

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Ann Arbor?

Yes, this clinical trial (NCT03687814) has an active research site in Ann Arbor, MI that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Irritable Bowel Syndrome Characterized by Constipation Treatment Options in Ann Arbor, MI

If you're searching for irritable bowel syndrome characterized by constipation treatment options in Ann Arbor, MI, this clinical trial (NCT03687814) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Ann Arbor research site is actively enrolling participants for this clinical trial. You'll receive care from experienced irritable bowel syndrome characterized by constipation specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all irritable bowel syndrome characterized by constipation clinical trials near you to find additional studies recruiting in your area.

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