Jacksonville, FLNCT05796388Now EnrollingIRB Ready

Irritable Bowel Syndrome With Constipation Clinical Trial in Jacksonville, FL

Access cutting-edge irritable bowel syndrome with constipation treatment through this clinical trial at a research site in Jacksonville. Study-provided care at no cost to qualified participants.

Sponsored by Mayo Clinic

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Expert Care in Jacksonville

Access irritable bowel syndrome with constipation specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related irritable bowel syndrome with constipation treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Jacksonville

    Convenient for FL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Jacksonville site if eligible
  4. 4Begin participation

About This Irritable Bowel Syndrome With Constipation Study in Jacksonville

The purpose of this study is to determine if adult patients with IBS-C will report an overall greater improvement in IBS symptoms and quality of life when treated with a combination of linaclotide (standard of care medication) and immersive virtual reality (VR) therapy compared to those treated with linaclotide and sham (placebo) VR therapy.

Sponsor: Mayo Clinic

Who Can Participate

Inclusion Criteria

Adult men and women (18-70) who meet Rome IV criteria for IBS-C.
Patients will be required to score below 65 points on the IBS Quality of Life (IBS-QOL) instrument, indicating a score consistent with at least moderate HRQOL (Health-related quality of life) impairment.

Exclusion Criteria

Patients will be excluded from the study if they have a comorbid disorder that may confound the diagnosis of IBS, including celiac disease, inflammatory bowel disease, autoimmune disorders that affect the GI system, history of bowel resection, HIV/AIDS, diabetes with HgA1c \>7.0, neuroendocrine tumors, microscopic colitis, lactase deficiency, eosinophilic bowel disease, acute intermittent porphyria, or any other condition that a licensed physician believes can mimic IBS symptoms and undermine diagnostic certitude.
Patients with severe depression, defined as a score equal to or greater than two standard deviations (SDs) on the NIH PROMIS depression scale, or those with suicidal ideations, will also be excluded and provided with standard resources to support their mental health and referred back to their primary care provider, a member of the study team will follow up with the PCP to ensure the communication was received.
Patients using regular doses of opioid medications will also be excluded given the often-severe impact of opioids on GI motility and potential for pharmacological visceral hyperalgesia.
Patients will also be excluded from the study if they do not meet Rome IV criteria for IBS-C,
have a known seizure disorder,
if symptoms are thought to represent an organic disorder,
if they have had prior surgery to the colon,
if symptoms represent a known pelvic floor disorder,
if the patient is abusing alcohol,
or if the patient cannot actively participate in the study for any other reason (e.g., inability to understand English as the VR program is in English only).
Patients previously treated with linaclotide who reported side effects,
those currently on linaclotide (any dose),
and those who did not note an improvement in IBS-C symptoms in the past while on linaclotide will also be excluded.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Jacksonville?

Yes, this clinical trial (NCT05796388) has an active research site in Jacksonville, FL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Irritable Bowel Syndrome With Constipation Treatment Options in Jacksonville, FL

If you're searching for irritable bowel syndrome with constipation treatment options in Jacksonville, FL, this clinical trial (NCT05796388) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Jacksonville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced irritable bowel syndrome with constipation specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all irritable bowel syndrome with constipation clinical trials near you to find additional studies recruiting in your area.

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