Portland, ORNCT03504800Now EnrollingIRB Ready

Keratoconus Clinical Trial in Portland, OR

Access cutting-edge keratoconus treatment through this clinical trial at a research site in Portland. Study-provided care at no cost to qualified participants.

Sponsored by Oregon Health and Science University

Quick Self-Assessment

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Expert Care in Portland

Access keratoconus specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related keratoconus treatment provided free

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Check if you qualify for this keratoconus clinical trial in Portland, OR

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Portland

    Convenient for OR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Portland site if eligible
  4. 4Begin participation

About This Keratoconus Study in Portland

This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions. The primary goal will be achieved by using optical coherence tomography (OCT) to: 1. Develop an OCT-based system to classify and evaluate corneal-shape irregularities. 2. Develop OCT metrics for more sensitive detection of keratoconus progression. 3. Develop OCT-and-topography guided phototherapeutic keratectomy (PTK) for irregular corneas.

Sponsor: Oregon Health and Science University

Who Can Participate

Inclusion Criteria

Keratoconus:
CDVA ≥ 20/25 in the better eye; and both of the following in the worse eye
Topography characteristic of keratoconus or pellucid marginal degeneration
Contact lens-related corneal warpage:
Contact lens use; and
Topography irregularities
Symptoms of dry eye documented by Ocular Surface Disease Index (OSDI) questionnaire score ≥ 30; and
Topography irregularities
Presence of punctate epithelial erosion on exam with surface staining
Aqueous deficiency or evaporative dry eye
Epithelial basement membrane dystrophy (EBMD):
Negative corneal fluorescein staining; and
Corneal opacities; and
Topography irregularities
Stromal addition or subtraction:
Salzmann's degeneration; or
Stromal dystrophies; or
Complication (visual complaints) after LASIK or photorefractive keratectomy (PRK)
Stromal distortion:
Radial keratectomy (RK); or
Corneal transplants.
Normal controls:
Healthy eyes with no previous eye procedures/surgeries. GROUP B: Participants will be selected from the keratoconus population in Group A based on topography findings. GROUP C: Participants will be selected from the stromal addition/subtraction and stromal distortion populations of Group A if they have vision primarily limited by scars, dystrophy, or high astigmatism that could benefit from PTK.

Exclusion Criteria

(all groups):
Inability to give informed consent.
Inability to maintain fixation for OCT imaging.
Inability to commit to required study visits.
Eyes with concurrent cataract, retinal disease, glaucoma, or other eye conditions that may limit the visual outcome after surgery.
Previous corneal surgeries if considered as a keratoconus participant.
Pregnancy or breastfeeding.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Portland?

Yes, this clinical trial (NCT03504800) has an active research site in Portland, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Keratoconus Treatment Options in Portland, OR

If you're searching for keratoconus treatment options in Portland, OR, this clinical trial (NCT03504800) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Portland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced keratoconus specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all keratoconus clinical trials near you to find additional studies recruiting in your area.

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