Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Keratoconus Clinical Trials
Keratoconus clinical trials are recruiting across 21 cities. Here are the cities with the most active studies:
Keratoconus Trial Phases
11 research organizations are sponsoring keratoconus trials.
About Keratoconus
Keratoconus is a progressive eye condition in which the cornea thins and bulges into a cone shape, causing blurry vision and light sensitivity. It typically begins in the teenage years. Treatment includes corneal cross-linking to halt progression, specialty contact lenses, and corneal transplant.
Clinical trials are advancing new treatments for keratoconus. Currently, 15 studies are recruiting a combined 23,416 participants across the United States. Research is being conducted by 11 organizations including University Hospital, Geneva, Price Vision Group, Goodman Eye Center and 8 others.
2026 Keratoconus Research Landscape
As of July 2026, the keratoconus clinical trial landscape includes 15 actively recruiting studies across 21 cities in the United States. These studies are collectively seeking 23,416 participants, with an average enrollment target of 1,561 per study.
The research spans multiple phases of development: 5 studies are in PHASE2, 2 studies are in PHASE3, 2 studies are in PHASE1, 2 studies are in NA, 1 study is in PHASE4. The presence of Phase 3 trials indicates that some keratoconus treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 11 different organizations, including University Hospital, Geneva, Price Vision Group, Goodman Eye Center, Woolfson Eye Institute, Oregon Health and Science University, and 6 others. The large number of sponsors reflects significant research interest and investment in keratoconus treatment advancement.
Geographically, keratoconus trials are most concentrated in Portland, Oregon (3 trials); Westerville, Ohio (3 trials); Boston, Massachusetts (2 trials); Los Angeles, California (1 trial); Indianapolis, Indiana (1 trial) and 7 other cities.
Featured Keratoconus Studies
Highlighted recruiting studies for keratoconus, selected by enrollment size and research scope.
The K-Map Study, Global Prevalence of KC
Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects patients at young age and can cause severe visual loss. The overall goal of this study is to assess the prevalence of keratoconus (KC) in children and adolescents in various regions of the world based on modern tomographic imaging methods, and ...
Comparison of Standard vs. Accelerated Corneal Crosslinking
The study objective is to compare accelerated and standard corneal crosslinking for treatment of progressive keratoconus or corneal ectasia.
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia
To evaluate the safety and effectiveness of the PXL Platinum 330 system for performing corneal cross-linking (CXL) for the treatment of ectatic disorders.
Frequently Asked Questions About Keratoconus Clinical Trials
Are there keratoconus clinical trials near me?
Yes, there are 15 keratoconus clinical trials currently recruiting across 21+ cities in the United States, including Portland, Oregon; Westerville, Ohio; Boston, Massachusetts. Browse the studies above to find one at a location convenient for you.
How do I join a keratoconus clinical trial?
To join a keratoconus clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are keratoconus clinical trials free?
Yes, participation in keratoconus clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of keratoconus treatments are being studied?
Current keratoconus clinical trials are testing a range of approaches across PHASE2 (5 studies), PHASE3 (2 studies), PHASE1 (2 studies), NA (2 studies), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 11 research organizations.
Is it safe to participate in keratoconus clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 15, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 15, 2026 · Data from ClinicalTrials.gov