A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will also learn about the saf...
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study ...
Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC
This is a multicenter, 2-arm, randomized, prospective study of patients slated for bilateral cataract extraction. One eye will be randomized to the Study Arm, and the fellow eye will be randomized to ...
Top Cities for Cataracts Clinical Trials
Cataracts clinical trials are recruiting across 14 cities. Here are the cities with the most active studies:
About Cataracts
Cataracts are a clouding of the eye's natural lens that leads to decreased vision and is the leading cause of blindness worldwide. They typically develop slowly with age. Surgery to remove the cloudy lens and replace it with an artificial one is highly effective.
Clinical trials are advancing new treatments for cataracts. Currently, 3 studies are recruiting a combined 942 participants across the United States. Research is being conducted by 3 organizations including Melt Pharmaceuticals, Berkeley Eye Center, Inder Paul Singh, M.D..
2026 Cataracts Research Landscape
As of March 2026, the cataracts clinical trial landscape includes 3 actively recruiting studies across 14 cities in the United States. These studies are collectively seeking 942 participants, with an average enrollment target of 314 per study.
Research is being led by 3 different organizations, including Melt Pharmaceuticals, Berkeley Eye Center, Inder Paul Singh, M.D..
Geographically, cataracts trials are most concentrated in Chico, California (1 trial); Grand Junction, Colorado (1 trial); Jacksonville, Florida (1 trial); Hagerstown, Maryland (1 trial); Alexandria, Minnesota (1 trial) and 7 other cities.
Featured Cataracts Studies
Highlighted recruiting studies for cataracts, selected by enrollment size and research scope.
A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)
The goal of this clinical trial is to learn if MELT-300 works on procedural sedation in adult participants undergoing cataract extraction with lens replacement (CELR). It will also learn about the safety of MELT-300. Researchers will compare MELT-300 to a placebo (a look-alike substance that contains no drug) to see if MELT-300 works on procedural sedation in adult participants undergoing CELR. Re...
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1 data.
Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC
This is a multicenter, 2-arm, randomized, prospective study of patients slated for bilateral cataract extraction. One eye will be randomized to the Study Arm, and the fellow eye will be randomized to the Control Arm.
Frequently Asked Questions About Cataracts Clinical Trials
Are there cataracts clinical trials near me?
Yes, there are 3 cataracts clinical trials currently recruiting across 14+ cities in the United States, including Chico, California; Grand Junction, Colorado; Jacksonville, Florida. Browse the studies above to find one at a location convenient for you.
How do I join a cataracts clinical trial?
To join a cataracts clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are cataracts clinical trials free?
Yes, participation in cataracts clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of cataracts treatments are being studied?
Current cataracts clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 3 research organizations.
Is it safe to participate in cataracts clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov