A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants Following Anti-inflammatory Treatment
This study aims to evaluate the performance of biomarkers and their responsiveness to standard-of-care treatments (Vevye® or Xiidra®), in participants with dry eye disease (DED) compared to healthy vo...
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye....
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses...
A Study in the Treatment of Mild to Moderate Dry Eye Disease Comparing Saline to TTAX03.
The purpose of this randomized, controlled, multicenter study is to evaluate the safety and efficacy of TTAX03 in participants with mild to moderate DED. The primary question it aims to answer is if ...
Top Cities for Dry Eye Clinical Trials
Dry Eye clinical trials are recruiting across 23 cities. Here are the cities with the most active studies:
About Dry Eye
Dry eye disease is a common condition that occurs when tears are unable to provide adequate lubrication for the eyes. It affects millions of people and can cause discomfort and vision problems. Treatment includes artificial tears, prescription eye drops, and procedures to conserve tears.
Clinical trials are advancing new treatments for dry eye. Currently, 4 studies are recruiting a combined 682 participants across the United States. Research is being conducted by 4 organizations including Hoffmann-La Roche, Vanda Pharmaceuticals, Bausch & Lomb Incorporated and 1 others.
2026 Dry Eye Research Landscape
As of March 2026, the dry eye clinical trial landscape includes 4 actively recruiting studies across 23 cities in the United States. These studies are collectively seeking 682 participants, with an average enrollment target of 171 per study.
Research is being led by 4 different organizations, including Hoffmann-La Roche, Vanda Pharmaceuticals, Bausch & Lomb Incorporated, BioTissue Holdings, Inc.
Geographically, dry eye trials are most concentrated in Memphis, Tennessee (2 trials); Lynchburg, Virginia (2 trials); Shelby, North Carolina (2 trials); Louisville, Kentucky (1 trial); Newport Beach, California (1 trial) and 7 other cities.
Featured Dry Eye Studies
Highlighted recruiting studies for dry eye, selected by enrollment size and research scope.
A Study to Explore Signs, Symptoms, and Biomarkers in Dry Eye Disease Participants Following Anti-inflammatory Treatment
This study aims to evaluate the performance of biomarkers and their responsiveness to standard-of-care treatments (Vevye® or Xiidra®), in participants with dry eye disease (DED) compared to healthy volunteers (control participants).
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
The purpose of this study is to determine the safety and efficacy of VSJ-110 compared to placebo in the treatment of dry eye.
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Assess the impact of concomitant Miebo use while wearing contact lenses
Frequently Asked Questions About Dry Eye Clinical Trials
Are there dry eye clinical trials near me?
Yes, there are 4 dry eye clinical trials currently recruiting across 23+ cities in the United States, including Memphis, Tennessee; Lynchburg, Virginia; Shelby, North Carolina. Browse the studies above to find one at a location convenient for you.
How do I join a dry eye clinical trial?
To join a dry eye clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are dry eye clinical trials free?
Yes, participation in dry eye clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of dry eye treatments are being studied?
Current dry eye clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in dry eye clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 1, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 1, 2026 · Data from ClinicalTrials.gov