Eugene, ORNCT03918408Now EnrollingIRB Ready

Keratoconus, Unstable Clinical Trial in Eugene, OR

Access cutting-edge keratoconus, unstable treatment through this phase 1 clinical trial at a research site in Eugene. Study-provided care at no cost to qualified participants.

Sponsored by Pacific Clear Vision Institute

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Expert Care in Eugene

Access keratoconus, unstable specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related keratoconus, unstable treatment provided free

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Check if you qualify for this keratoconus, unstable clinical trial in Eugene, OR

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Why Participate?

  • No-Cost Study Care

  • Local to Eugene

    Convenient for OR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Eugene site if eligible
  4. 4Begin participation

About This Keratoconus, Unstable Study in Eugene

To determine whether the Peschke PXL-330 system is safe and effective in the treatment of corneal thinning conditions.

Sponsor: Pacific Clear Vision Institute

Who Can Participate

Inclusion Criteria

Subjects who have one or both eyes that meet criteria 1 \& 2 and 1 or more of the following criteria will be considered candidates for this study.
12 years of age or older
Evidence of progressive keratoconus (based on the discretion of the physician as evidenced by an increase in astigmatism, asymmetry, or worsening vision in the last 3 or more months)
Presence of central or inferior steepening.
Axial topography consistent with keratoconus
Presence of one or more findings associated with keratoconus such as:
Fleischer ring
Vogt's striae
Decentered corneal apex
Munson's sign
Rizzutti's sign
Apical Corneal scarring consistent with Bowman's breaks
Scissoring of the retinoscopic reflex
Crab-claw appearance on topography
Steepest keratometry (Kmax) value ≥ 47.20 D
I-S keratometry difference \> 1.5 D on the Pentacam/Galilei/Orbscan/Cassini map or topography map
Posterior corneal elevation \>16 microns
Thinnest corneal point \<485 microns
AvaGen (Avellino Labs) genetic testing keratoconus risk score of 67 or higher (high risk).
Signed written informed consent
Willingness and ability to comply with schedule for follow-up visits
For Contact Lens Wearers Only: Removal of contact lenses for the required period of time prior to the screening refraction:
Contact Lens Type Minimum Discontinuation Time:
Soft: 1 Week
Soft Extended Wear: 2 Weeks
Soft Toric: 3 Weeks
Rigid gas permeable: 2 Weeks per decade of wear
Scleral Lenses
Investigator Discretion \[Discontinuation of scleral lenses not required unless there is clinical evidence of corneal hypoxia (e.g. corneal neovascularization) at time of screening\]
Signed written informed consent
Willingness and ability to comply with schedule for follow-up visits

Exclusion Criteria

(any of the following are reasons for exclusion):
Eyes classified as either normal or atypical normal on the severity grading scheme.
Corneal pachymetry at the screening exam that is \<330 microns at the thinnest point in the eye(s) to be treated.
Previous ocular condition (other than refractive error) in the eye(s) to be treated that may predispose the eye for future complications, for example:
History of or active corneal disease (e.g., herpes simplex, herpes zoster keratitis, recurrent erosion syndrome, acanthomeoeba, etc.)
Clinically significant corneal scarring in the CXL treatment zone that is not related to keratoconus or, in the investigator's opinion, will interfere with the cross-linking procedure.
Pregnancy (including plan to become pregnant) or lactation during the course of the study
A known sensitivity to study medications
Patients with nystagmus or any other condition that would prevent a steady gaze during the CXL treatment or other diagnostic tests.
Patients with active medical implants (e.g. cardiac pacemakers)'
Patients who are aphakic/ pseudophakic

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Eugene?

Yes, this clinical trial (NCT03918408) has an active research site in Eugene, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Keratoconus, Unstable Treatment Options in Eugene, OR

If you're searching for keratoconus, unstable treatment options in Eugene, OR, this clinical trial (NCT03918408) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Eugene research site is actively enrolling participants for this phase 1 clinical trial. You'll receive care from experienced keratoconus, unstable specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all keratoconus, unstable clinical trials near you to find additional studies recruiting in your area.

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