San Deigo, CANCT06999577Now EnrollingIRB Ready

Laryngopharyngeal Reflux Clinical Trial in San Deigo, CA

Access cutting-edge laryngopharyngeal reflux treatment through this clinical trial at a research site in San Deigo. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Diego

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Expert Care in San Deigo

Access laryngopharyngeal reflux specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related laryngopharyngeal reflux treatment provided free

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Check if you qualify for this laryngopharyngeal reflux clinical trial in San Deigo, CA

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Why Participate?

  • No-Cost Study Care

  • Local to San Deigo

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit San Deigo site if eligible
  4. 4Begin participation

About This Laryngopharyngeal Reflux Study in San Deigo

The goal of this clinical trial is to learn if a mechanism guided strategy that utilizes a multidisciplinary approach to treat adults patients (age 18-89) with chronic throat symptoms who are undergoing clinical evaluation for laryngopharyngeal reflux (LPR) is more effective than the usual care strategy with proton pump inhibitor (PPI) therapy used in gastroenterology for these patients. The main question it aims to answer is: Will a greater proportion of the mechanism guided strategy participants achieve symptom response in comparison to the usual care strategy participants? If there is a comparison group: Researchers will compare the mechanism guided strategy to usual care strategy to see if treatment response differs between the groups. Participants will be be asked to do the following: * participate in an 8-week blinded study phase where they will be randomized to either 1) Mechanism Guided Strategy or 2) Usual Care Strategy * take an oral capsule daily (omeprazole 40mg or placebo) * come to 3 in-person visits at UC San Diego Health for an intervention visit with a study provider * consider incorporating recommended lifestyle modifications * complete weekly surveys

Sponsor: University of California, San Diego

Who Can Participate

Inclusion Criteria

18-89 years of age
\>8 weeks of laryngeal symptoms (cough, throat clearing, dysphonia)
Standard evaluation for LPR, undergoing EGD (with endoscopic evaluation of the hypopharynx) and reflux monitoring off acid suppression
Off acid suppression therapy for at least 2 weeks prior to randomization.

Exclusion Criteria

PPI intolerance and/or known hypersensitivity to the formulation or substituted benzimidazoles
History of foregut surgery
Known diagnosis of achalasia
Inability to fast for 4 hours (no food or drink)
Active tobacco use
Pregnant or breastfeeding
Unable to consent in English or Spanish
Unable to provide consent without a legal guardian or representative
Endoscopic findings conclusive with esophageal mucosal abnormalities
Unable to proceed with reflux monitoring
Use of acid suppression during the reflux monitoring and/or before the study medication (omeprazole or placebo) is dispensed
Prior LRT for reflux related symptoms
History of major psychiatric comorbidity
Unable to attend in person study visits at UCSD

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in San Deigo?

Yes, this clinical trial (NCT06999577) has an active research site in San Deigo, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Laryngopharyngeal Reflux Treatment Options in San Deigo, CA

If you're searching for laryngopharyngeal reflux treatment options in San Deigo, CA, this clinical trial (NCT06999577) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our San Deigo research site is actively enrolling participants for this clinical trial. You'll receive care from experienced laryngopharyngeal reflux specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all laryngopharyngeal reflux clinical trials near you to find additional studies recruiting in your area.

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