La Jolla, CANCT06824974Now EnrollingIRB Ready

Liver Cancer, Adult Clinical Trial in La Jolla, CA

Access cutting-edge liver cancer, adult treatment through this clinical trial at a research site in La Jolla. Study-provided care at no cost to qualified participants.

Sponsored by University of California, San Diego

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Expert Care in La Jolla

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related liver cancer, adult treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to La Jolla

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit La Jolla site if eligible
  4. 4Begin participation

About This Liver Cancer, Adult Study in La Jolla

This is a feasibility study that will collect data to assess the potential effect of nutritional intervention. This prospective single-site trial will enroll adult patients with liver diseases such as metabolic-dysfunction associated steatotic liver disease (MASLD), metabolic-dysfunction associated steatohepatitis (MASH), cirrhosis and/or hepatocellular carcinoma (HCC). Eligible individuals who are randomized to the intervention group will be enrolled in a six-month nutritional change program consisting of time-restricted eating plus targeted healthy changes in what they eat (TR-HE). The intervention includes dietary counseling visits with a study registered dietitian (RD) and motivational phone calls with a study Certified Health and Wellness Coach (HC). Individuals who are randomized to the control group or who elect to join the control group will be enrolled in a six-month period of observation and phlebotomy only. The main questions it aims to answer are: Is a prolonged nightly fast coupled with a healthy diet safe and feasible for patients with liver disease or cancer? Does the intervention improve liver metabolism?

Sponsor: University of California, San Diego

Who Can Participate

Inclusion Criteria

Overweight or obese (BMI 27-45 kg/m2)
Diagnosed with metabolic-dysfunction associated steatitic liver disease (MASLD/NAFLD), metabolic-dysfunction associated steatohepatitis, cirrhosis or liver cancer (BCLC early to intermediate stage HCC)
English or Spanish speaking over the age of 18.
ECOG Performance Status ≤ 2.
Usual nightly fasting \<12 hours
Willing to comply with all study procedures
Life expectancy of \> 12 months

Exclusion Criteria

Advanced HCC, progression, and/or associated comorbidities
Metastatic disease, tumor in vein, or ascites
Advanced Cirrhosis (hypoalbuminemia/Child-Pugh B+C).
Poorly controlled or refractory (grade 3-4) hepatic encephalopathy
Type 1 diabetes or self-reported hypoglycemia or hypoglycemic events by CGM
Participation in another conflicting study that requires modification of diet or food timing.
Patients on GLP-1 receptor agonists
Uncontrollable eating pattern (e.g., wasting, Night Eating Syndrome, disordered eating habits, food insecurity)
Medications that markedly impact metabolic study biomarkers.
Other cancer in last 10 years (other than nonmelanoma skin cancer or carcinoma of the cervix in situ)
Serious medical conditions such as chronic kidney disease, congestive heart failure, or any condition that would interfere with participation in the trial.
Unresolved toxicity ≥ CTCAE Grade 2 from previous anti-cancer therapy
Active alcohol abuse or less than 6 months of sobriety
Participation in a trial of an investigational agent within the prior 30 days
Pregnancy or lactating, positive hCG urine test.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in La Jolla?

Yes, this clinical trial (NCT06824974) has an active research site in La Jolla, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Liver Cancer, Adult Treatment Options in La Jolla, CA

If you're searching for liver cancer, adult treatment options in La Jolla, CA, this clinical trial (NCT06824974) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our La Jolla research site is actively enrolling participants for this clinical trial. You'll receive care from experienced liver cancer, adult specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all liver cancer, adult clinical trials near you to find additional studies recruiting in your area.

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