NCT07130812 · Loma Linda University
Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.
What this study is about
The purpose of this graduate student research study is to compare the effects of low-load blood flow restriction training (LL-BFR) and heavy-load training (HLT) in high-volume rowers with mild low back pain or recurrent low back pain (LBP), aiming to determine whether LL-BFR offers a safer yet equally effective alternative to HLT for enhancing performance and reducing risk of re-injury.
View original scientific description
The purpose of this graduate student research study is to compare the effects of low-load blood flow restriction training (LL-BFR) and heavy-load training (HLT) in high-volume rowers with mild low back pain or recurrent low back pain (LBP), aiming to determine whether LL-BFR offers a safer yet equally effective alternative to HLT for enhancing performance and reducing risk of re-injury.
Interventions
OTHER
blood flow restriction
The SAGA blood flow restriction tourniquet system will be used for each training sessions for the rowers within the light load restriction group. The 4 inch-wide tourniquet will be applied to both upper thighs during the strength and endurance exercises. Tourniquet setting will be determined as the pressure needed to achieve 40-80% arterial occlusion to the extremity (as measured by the SAGA BFR unit). The SAGA units provides a consistent amount of pressure to the extremity throughout the ROM of the exercise. The settings will be determined at baseline and then recalibrated weekly.
OTHER
Heavy load resistance training
For the resistance prescription, rowers will do strengthening exercises at 70-80% 1 RM. Exercises will be performed in series following 6 sets by 5 reps, with 120 seconds of rest between sets for each exercise.
Primary outcome measures
Hamstring and quadricep muscular fatigue assessment via Noraxon Electromyography
Time frame: change between baseline and 10 weeks
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Aged 13-20 years old
- Currently active rower (training ≥3 days/week or 12 hours/week)
- Mild LBP with a low reactivity (\<3/10) or recurring LBP within the past 18 months that has affected attendance to team practices/races.
- Able to complete a 2,000-meter rowing erg test
Exclusion criteria
- Have severe or acute back pain that limits basic movement or requires medical treatment
- History of spinal surgery or structural spine conditions (scoliosis requiring bracing/surgery)
- Have a contraindication to BFR training, identified via BFR safety screening form:
- Peripheral vascular disease (PVD)
- History of vascular surgery in arms or legs
- Skin grafts on arms or legs
- Arteriovenous fistula in limbs
- Cognitive or physical impairment that limits participation
- Hypertension or high blood pressure (uncontrolled or undiagnosed)
- Bleeding disorders (e.g., hemophilia)
- Blood clotting disorders (e.g., lupus, factor-V Leiden)
- Past history of DVT or pulmonary embolism (PE)
- Surgery in the past 12 weeks
- Recent limb immobilization (e.g., cast, boot) in the last 4 weeks
- History of stroke or transient ischemic attack (TIA)
- History of cancer
- Diagnosed heart disease
- History of rhabdomyolysis
- Diagnosed diabetes
- Sickle cell disease
- History of compartment syndrome
- History of nerve damage or injury
- Any prior complications or adverse reactions to BFR training
- Any other medical conditions that should be cleared by a physician before starting BFR
- Pregnancy(Self-reported)
Where
- Loma Linda, California
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Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced May 18, 2026 · Source of record for eligibility and locations