Columbus, OHNCT07434869Now EnrollingIRB Ready

Lung Transplant Failure and Rejection Clinical Trial in Columbus, OH

Access cutting-edge lung transplant failure and rejection treatment through this clinical trial at a research site in Columbus. Study-provided care at no cost to qualified participants.

Sponsored by Brian Keller

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Expert Care in Columbus

Access lung transplant failure and rejection specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related lung transplant failure and rejection treatment provided free

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Check if you qualify for this lung transplant failure and rejection clinical trial in Columbus, OH

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Why Participate?

  • No-Cost Study Care

  • Local to Columbus

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Columbus site if eligible
  4. 4Begin participation

About This Lung Transplant Failure and Rejection Study in Columbus

This study is for people who have had a lung transplant and developed a condition called chronic lung allograft dysfunction (CLAD), which is a type of chronic rejection. Doctors often treat CLAD with a procedure called extracorporeal photopheresis (ECP), but it can take up to six months to know if the treatment is working. The goal of the study is to find early signs (biomarkers) that show whether ECP is helping, so patients can get the right care sooner. For participants in the study, small blood samples will be collected at three points during ECP treatment and, for some participants, two MRI scans of the lungs will be performed-one before starting ECP and one after finishing treatment. The MRI uses a safe contrast dye to help us see changes in lung blood flow and tissue. Investigators will also look at certain immune cells in the blood. This is not a study of a new drug or treatment-participants will receive the same ECP therapy their doctor already recommended. The study will help researchers understand how ECP works and identify markers that predict who benefits most. There is no direct benefit to participants, but participation may help improve care for future lung transplant patients.

Sponsor: Brian Keller

Who Can Participate

Inclusion Criteria

Adults (≥18 years) or pediatric patients (7-17 years) who have had a single or double lung transplant
Diagnosed with CLAD (any stage) and prescribed ECP therapy
Ability to provide informed consent (or assent with parental consent for minors)

Exclusion Criteria

Previously received ECP treatment
Receipt of anti-thymocyte globulin within 3 months or alemtuzumab within 12 months of ECP initiation
Contraindications to MRI (for MRI subgroup), including metal implants, claustrophobia, seizure disorder
Known allergy to gadolinium or impaired kidney function (eGFR \<30 ml/min)
Pregnant or breastfeeding

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Columbus?

Yes, this clinical trial (NCT07434869) has an active research site in Columbus, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Lung Transplant Failure and Rejection Treatment Options in Columbus, OH

If you're searching for lung transplant failure and rejection treatment options in Columbus, OH, this clinical trial (NCT07434869) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Columbus research site is actively enrolling participants for this clinical trial. You'll receive care from experienced lung transplant failure and rejection specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all lung transplant failure and rejection clinical trials near you to find additional studies recruiting in your area.

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