Palo Alto, CANCT05825157Now EnrollingIRB Ready

Lymphedema Arm Clinical Trial in Palo Alto, CA

Access cutting-edge lymphedema arm treatment through this clinical trial at a research site in Palo Alto. Study-provided care at no cost to qualified participants.

Sponsored by Stanford University

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Expert Care in Palo Alto

Access lymphedema arm specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related lymphedema arm treatment provided free

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Check if you qualify for this lymphedema arm clinical trial in Palo Alto, CA

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Why Participate?

  • No-Cost Study Care

  • Local to Palo Alto

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Palo Alto site if eligible
  4. 4Begin participation

About This Lymphedema Arm Study in Palo Alto

Investigate whether the addition of the Biobridge scaffold to the standard surgery for vascularized lymph node transfer will improve the outcome of surgical treatment in lymphedema of the upper extremity. Will Biobridge improve upon the low success rate of the currently practiced surgery by facilitating the lymphatic connections to the transplanted node that are crucial to its viability and function.

Sponsor: Stanford University

Who Can Participate

Inclusion Criteria

Ages 18 to 75 years (inclusive)
Life expectancy \> 2 years
Upper limb lymphedema
The participant must be eligible for surgical intervention
Swelling of 1 limb that is not completely reversed by elevation or compression
Stage I-II lymphedema at screening, based on the International Society of Lymphology (ISL) staging system
Participants with a history of cancer must have no evidence of disease (NED), have completed breast cancer therapy 3 years prior to enrollment; use of endocrine therapy is allowed.
Completion of a full course of complete decongestive therapy (CDT), according to ISL guidelines at least 12 weeks prior to screening, including use of compression garments for at least 12 weeks without change in regimen
Willingness to comply with recommended regimen of self care, with consistent use of compression garments from screening through the entire study duration (through the safety follow up visit), excluding the first 3 weeks postoperatively where patients are required to not wear compression. Self bandaging, use of nighttime compression garments, and intermittent pneumatic compression devices are allowed, but the procedures and regimens are expected to remain consistent from screening though the entire study duration.
Consistent use of an appropriately sized compression garment for daytime use.
Limb volume (LV) in the affected limb and unaffected limb must be at least 10% of each other.
Evidence of abnormal bioimpedance ratio, if feasible, based upon unilateral disease: L Dex \> 10 units.
Willingness and ability to comply with all study procedures, including measurement of limb volume, skin biopsy, and preoperative and postoperative imaging studies.
Willingness and ability to understand, and to sign a written informed consent form document

Exclusion Criteria

Edema arising from increased capillary filtration will be excluded (venous incompetence).
Inability to safely undergo general anesthesia and/or perioperative care related to vascularized lymph node transfer
Concurrent participation in a clinical trial of any other investigational drug or therapy, regardless of indication, within 1 month before screening or 5 times the drug's half life, whichever is longer
Recent initiation (≤ 12 weeks) of CDPT for lymphedema
Other medical condition that could lead to acute limb edema, such as (but not limited to) acute venous thrombosis or heart failure
Other medical condition that could result in symptoms overlapping those of lymphedema in the affected limb (e.g., pain, swelling, decreased range of motion)
History of clotting disorder (hypercoagulable state)
Chronic (persistent) infection in the affected limb
Infection of the lymphedema limb within 1 month prior to screening
Currently receiving chemotherapy or radiation therapy
Body Mass Index (BMI) \>35
Known sensitivity to porcine products
Anaphylaxis to iodine
Pregnancy or nursing
Substance abuse (such as alcohol or drug abuse) within 6 months prior to screening
Any reason (in addition to those listed above) that, in the opinion of the investigator, precludes full participation in the study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Palo Alto?

Yes, this clinical trial (NCT05825157) has an active research site in Palo Alto, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Lymphedema Arm Treatment Options in Palo Alto, CA

If you're searching for lymphedema arm treatment options in Palo Alto, CA, this clinical trial (NCT05825157) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Palo Alto research site is actively enrolling participants for this clinical trial. You'll receive care from experienced lymphedema arm specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all lymphedema arm clinical trials near you to find additional studies recruiting in your area.

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