Recruiting Studies
Advanced SearchData: ClinicalTrials.gov · Source of record for eligibility and locations
Top Cities for Lymphedema Clinical Trials
Lymphedema clinical trials are recruiting across 24 cities. Here are the cities with the most active studies:
Lymphedema Trial Phases
15 research organizations are sponsoring lymphedema trials.
About Lymphedema
Lymphedema is chronic swelling caused by a buildup of lymph fluid, most commonly in the arms or legs. It often occurs after cancer treatment that removes or damages lymph nodes. Management includes compression garments, manual lymphatic drainage, and decongestive therapy.
Clinical trials are advancing new treatments for lymphedema. Currently, 24 studies are recruiting a combined 14,477 participants across the United States. Research is being conducted by 15 organizations including Massachusetts General Hospital, Memorial Sloan Kettering Cancer Center, M.D. Anderson Cancer Center and 12 others.
2026 Lymphedema Research Landscape
As of July 2026, the lymphedema clinical trial landscape includes 24 actively recruiting studies across 24 cities in the United States. These studies are collectively seeking 14,477 participants, with an average enrollment target of 603 per study.
The research spans multiple phases of development: 13 studies are in NA, 3 studies are in EARLY_PHASE1, 2 studies are in PHASE2, 1 study is in PHASE3, 1 study is in PHASE4. The presence of Phase 3 trials indicates that some lymphedema treatments are in late-stage testing and may be approaching regulatory review.
Research is being led by 15 different organizations, including Massachusetts General Hospital, Memorial Sloan Kettering Cancer Center, M.D. Anderson Cancer Center, University Hospital, Basel, Switzerland, Abramson Cancer Center at Penn Medicine, and 10 others. The large number of sponsors reflects significant research interest and investment in lymphedema treatment advancement.
Geographically, lymphedema trials are most concentrated in New York, New York (5 trials); Houston, Texas (5 trials); Boston, Massachusetts (3 trials); Harrison, New York (3 trials); Philadelphia, Pennsylvania (3 trials) and 7 other cities.
Featured Lymphedema Studies
Highlighted recruiting studies for lymphedema, selected by enrollment size and research scope.
Prospective Screening for Breast Cancer-related Lymphedema
The primary objectives of this study are twofold: 1) to detect and determine the level of symptoms, functional disability, and changes in quality of life that breast cancer patients experience from changes in their arms during and after treatment for breast cancer by collecting patient reported outcome measures, objective measurements, and clinical information in a prospectively maintained databas...
Lymphedema Surveillance Study
This study is being done to find out how many women develop lymphedema after an axillary lymph node dissection. The investigators also want to look for reasons why some women get lymphedema and others don't. Specifically, the investigators want to do tests on the breast tissue that is removed at the time of surgery to see if they can identify inflammation in the breast tissue, which may increase a...
A Study Comparing Quality of Life in Patients With Lymphedema Who Undergo Surgical Treatment Versus Non-Surgical Management
This study is being done to see the long-term results for patients who choose to have surgery for lymphedema (with the vascularized lymph node transfer), compared to patients who choose not to have surgery.
Frequently Asked Questions About Lymphedema Clinical Trials
Are there lymphedema clinical trials near me?
Yes, there are 24 lymphedema clinical trials currently recruiting across 24+ cities in the United States, including New York, New York; Houston, Texas; Boston, Massachusetts. Browse the studies above to find one at a location convenient for you.
How do I join a lymphedema clinical trial?
To join a lymphedema clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are lymphedema clinical trials free?
Yes, participation in lymphedema clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of lymphedema treatments are being studied?
Current lymphedema clinical trials are testing a range of approaches across NA (13 studies), EARLY_PHASE1 (3 studies), PHASE2 (2 studies), PHASE3 (1 study), PHASE4 (1 study). These include new drugs, combination therapies, medical devices, and other interventions sponsored by 15 research organizations.
Is it safe to participate in lymphedema clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated July 17, 2026 from ClinicalTrials.gov
About This Data
Data: ClinicalTrials.gov · Source of record for eligibility and locations
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated July 17, 2026 · Data from ClinicalTrials.gov