Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
The purpose of this research is to determine the safety and efficacy of withdrawing MMF (Mycophenolate Mofetil) in kidney transplant recipients who are 55 years or older at the time of receiving a kid...
High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
Influenza virus is a significant pathogen in pediatric solid organ transplant (SOT) recipients. However, these individuals respond poorly to standard-dose (SD) inactivated influenza vaccine (IIV). Rec...
A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)
The main aim of this study is to find out the safety, tolerability and pharmacokinetics (PK) of maribavir for the treatment of CMV infection in children and teenagers after HSCT or SOT and to identify...
A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies
This Phase 1B/2 study is a multicenter, open-label, study of RP1 to investigate the (a) objective response rate, in addition to (b) safety and tolerability of RP1 for the treatment of advanced cutaneo...
Top Cities for Organ Transplant Clinical Trials
Organ Transplant clinical trials are recruiting across 25 cities. Here are the cities with the most active studies:
About Organ Transplant
Organ transplantation is a surgical procedure to replace a diseased organ with a healthy one from a donor. Managing rejection through immunosuppressive medications is a lifelong requirement. Research continues to improve outcomes through better immunosuppression, organ preservation, and xenotransplantation.
Clinical trials are advancing new treatments for organ transplant. Currently, 4 studies are recruiting a combined 807 participants across the United States. Research is being conducted by 4 organizations including Mayo Clinic, National Institute of Allergy and Infectious Diseases (NIAID), Takeda and 1 others.
2026 Organ Transplant Research Landscape
As of March 2026, the organ transplant clinical trial landscape includes 4 actively recruiting studies across 25 cities in the United States. These studies are collectively seeking 807 participants, with an average enrollment target of 202 per study.
Research is being led by 4 different organizations, including Mayo Clinic, National Institute of Allergy and Infectious Diseases (NIAID), Takeda, Replimune Inc..
Geographically, organ transplant trials are most concentrated in Phoenix, Arizona (3 trials); Chicago, Illinois (2 trials); Cincinnati, Ohio (2 trials); Houston, Texas (2 trials); Rochester, Minnesota (1 trial) and 7 other cities.
Featured Organ Transplant Studies
Highlighted recruiting studies for organ transplant, selected by enrollment size and research scope.
Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
The purpose of this research is to determine the safety and efficacy of withdrawing MMF (Mycophenolate Mofetil) in kidney transplant recipients who are 55 years or older at the time of receiving a kidney transplant. We are comparing them to patients who receive the standard of care Mycophenolate Mofetil.
High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients
Influenza virus is a significant pathogen in pediatric solid organ transplant (SOT) recipients. However, these individuals respond poorly to standard-dose (SD) inactivated influenza vaccine (IIV). Recent studies have investigated two strategies to overcome poor immune responses in SOT recipients: (1) administration of high-dose (HD)-IIV compared to SD-IIV and (2) two doses of SD-IIV compared to on...
A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)
The main aim of this study is to find out the safety, tolerability and pharmacokinetics (PK) of maribavir for the treatment of CMV infection in children and teenagers after HSCT or SOT and to identify the optimal dose of maribavir using a 200 milligrams (mg) tablet formulation or powder for oral suspension. The participants will be treated with maribavir for 8 weeks. Participants need to visit t...
Frequently Asked Questions About Organ Transplant Clinical Trials
Are there organ transplant clinical trials near me?
Yes, there are 4 organ transplant clinical trials currently recruiting across 25+ cities in the United States, including Phoenix, Arizona; Chicago, Illinois; Cincinnati, Ohio. Browse the studies above to find one at a location convenient for you.
How do I join a organ transplant clinical trial?
To join a organ transplant clinical trial: 1) Browse the available studies on this page, 2) Click on a study that interests you, 3) Check the study locations to find a site near you, 4) Review the eligibility criteria, and 5) Contact the study site or complete the eligibility form. The process is free and you can withdraw at any time.
Are organ transplant clinical trials free?
Yes, participation in organ transplant clinical trials is free. Study-related treatments, medical tests, and doctor visits are provided at no cost to participants. Many studies also offer compensation for your time and travel expenses.
What types of organ transplant treatments are being studied?
Current organ transplant clinical trials are testing a range of approaches. These include new drugs, combination therapies, medical devices, and other interventions sponsored by 4 research organizations.
Is it safe to participate in organ transplant clinical trials?
Clinical trials are carefully regulated by the FDA and institutional review boards (IRBs). All trials must follow strict safety protocols, and participants receive close medical monitoring throughout the study. You can withdraw from a trial at any time without penalty.
Data updated March 2, 2026 from ClinicalTrials.gov
About This Data
Clinical trial information on this page is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health (NIH) and National Library of Medicine (NLM). Study data is refreshed every hour to ensure accuracy.
Medical Disclaimer: The information provided on this page is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making decisions about clinical trial participation or changes to your treatment plan.
Page reviewed by the HelloStudys Research Team · Last updated March 2, 2026 · Data from ClinicalTrials.gov