Cleveland, OHNCT06344143Now EnrollingIRB Ready

Mild Autonomous Cortisol Secretion (MACS) Clinical Trial in Cleveland, OH

Access cutting-edge mild autonomous cortisol secretion (macs) treatment through this clinical trial at a research site in Cleveland. Study-provided care at no cost to qualified participants.

Sponsored by The Cleveland Clinic

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Expert Care in Cleveland

Access mild autonomous cortisol secretion (macs) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild autonomous cortisol secretion (macs) treatment provided free

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Check if you qualify for this mild autonomous cortisol secretion (macs) clinical trial in Cleveland, OH

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Why Participate?

  • No-Cost Study Care

  • Local to Cleveland

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cleveland site if eligible
  4. 4Begin participation

About This Mild Autonomous Cortisol Secretion (MACS) Study in Cleveland

The aim of the proposed study is to estimate the incidence of Mild Autonomous Cortisol Secretion (MACS) in patients with Adrenal Incidentaloma (AI) and evaluate the available diagnostic tests to determine the most sensitive and specific combination of tests for assessing MACS from adrenal adenoma for prediction of the phenotype associated with cortisol excess. As well as following the patients for 4 years and see if anything changes.

Sponsor: The Cleveland Clinic

Who Can Participate

Inclusion Criteria

Patients ages 18 years and older.
Presence of adrenal incidentaloma by cat scan (CT) or magnetic resonance imaging (MRI) examination.
1-mg Dexamethasone suppression test cortisol ≤ 5 μg/dL with adequate dexamethasone level.

Exclusion Criteria

1-mg Dexamethasone suppression test cortisol \> 5 μg/dL with adequate dexamethasone level. Patients who fail to suppress below this level will be considered to have Cushing's syndrome and will be referred for appropriate treatment.
Current or recent (3 months) history of use of glucocorticoid medication (including joint injections of steroids).
History of uncontrolled hypertension or history of hypertension with more than 2 medications.
History of uncontrolled type 2 Diabetes Mellitus or history of diabetes mellitus with A1c\>7.5.
Known History of osteoporosis
Documented Clinical Cushing's disease.
Clinical suspicion of adrenal carcinoma.
History of alcohol abuse/dependence.
History of cirrhosis of liver.
History of hepatitis B or C infection regardless of treatment.
History of type 1 diabetes.
History of hemochromatosis.
History of autoimmune hepatitis.
History of Wilson's disease.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cleveland?

Yes, this clinical trial (NCT06344143) has an active research site in Cleveland, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Autonomous Cortisol Secretion (MACS) Treatment Options in Cleveland, OH

If you're searching for mild autonomous cortisol secretion (macs) treatment options in Cleveland, OH, this clinical trial (NCT06344143) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cleveland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mild autonomous cortisol secretion (macs) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild autonomous cortisol secretion (macs) clinical trials near you to find additional studies recruiting in your area.

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