Pittsburgh, PANCT07573163Now EnrollingIRB Ready

Mild Autonomous Cortisol Secretion (MACS) Clinical Trial in Pittsburgh, PA

Access cutting-edge mild autonomous cortisol secretion (macs) treatment through this phase 2 clinical trial at a research site in Pittsburgh. Study-provided care at no cost to qualified participants.

Sponsored by Alaa Sada

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Expert Care in Pittsburgh

Access mild autonomous cortisol secretion (macs) specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild autonomous cortisol secretion (macs) treatment provided free

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Check if you qualify for this mild autonomous cortisol secretion (macs) clinical trial in Pittsburgh, PA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Pittsburgh

    Convenient for PA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Pittsburgh site if eligible
  4. 4Begin participation

About This Mild Autonomous Cortisol Secretion (MACS) Study in Pittsburgh

Mild Autonomous Cortisol Secretion (MACS) is a condition in which an adrenal gland produces excess cortisol and is associated with high blood pressure, diabetes, and weight gain. Surgical removal of the adrenal gland (adrenalectomy) is standard treatment, but some patients continue to have metabolic health problems after surgery. This randomized study will evaluate whether treatment with tirzepatide after adrenalectomy improves metabolic outcomes in patients with MACS compared with adrenalectomy alone.

Sponsor: Alaa Sada

Who Can Participate

Inclusion Criteria

Adults aged 18 years and older
Diagnosis of MACS, defined as morning cortisol \>1.8 mcg/dL after a 1 mg dexamethasone suppression test
Elevated blood pressure (SBP ≥120 mmHg or DBP ≥80 mmHg per the 2025 American College of Cardiology/American Heart Association \[ACC/AHA\] criteria, or current use of antihypertensive medication)
Undergoing or having undergone adrenalectomy for the treatment of MACS

Exclusion Criteria

Bilateral adrenal lesions
Adrenal malignancy
Concurrent primary aldosteronism with MACS
Current use of GLP-1 receptor agonists
Personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2)
Pregnancy or breastfeeding

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Pittsburgh?

Yes, this clinical trial (NCT07573163) has an active research site in Pittsburgh, PA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Autonomous Cortisol Secretion (MACS) Treatment Options in Pittsburgh, PA

If you're searching for mild autonomous cortisol secretion (macs) treatment options in Pittsburgh, PA, this clinical trial (NCT07573163) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Pittsburgh research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced mild autonomous cortisol secretion (macs) specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild autonomous cortisol secretion (macs) clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Pittsburgh, PA