Cincinnati, OHNCT07464886Now EnrollingIRB Ready

Mild Depression Clinical Trial in Cincinnati, OH

Access cutting-edge mild depression treatment through this phase 3 clinical trial at a research site in Cincinnati. Study-provided care at no cost to qualified participants.

Sponsored by University of Cincinnati

Quick Self-Assessment

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Expert Care in Cincinnati

Access mild depression specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild depression treatment provided free

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Check if you qualify for this mild depression clinical trial in Cincinnati, OH

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Cincinnati

    Convenient for OH residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Cincinnati site if eligible
  4. 4Begin participation

About This Mild Depression Study in Cincinnati

The primary goal is to investigate to what extent changes in glutamate and glutathione modulation and functional integration between brain networks associated with emotion and attention regulation are associated with treatment response in mildly depressed youth.

Sponsor: University of Cincinnati

Who Can Participate

Inclusion Criteria

age between 15 years, 0 months to 24 years, 11 months old;
presenting with mild depression, defined by meeting DSM-5 criteria for a current major depressive episode, mild severity, or persistent depressive disorder, or other specified depressive disorder (depressive episode with insufficient symptoms to meet criteria for a major depressive episode);
medication-naïve or medication free for at least 5 half-lives since the last use of a psychoactive medication, with the exception of stimulants for ADHD;
if on ADHD stimulant medication over 2 months prior to screening, willing to maintain stimulant dose constant during the study participation;
Tanner stage greater than or equal to III;

Exclusion Criteria

significant suicidal risk, defined by suicidal ideation of type 3, 4 or 5 on the Columbia Suicide Severity Rating Scale (C-SSRS) in the past 3 months, or any lifetime suicidal attempts;
current major depressive episode, moderate or severe
current or lifetime history of manic or hypomanic episodes, and/or diagnosis of bipolar disorder;
current or lifetime history of psychotic disorders, and/or prior diagnosis of schizophrenia spectrum disorders;
active or current substance use disorders in the last 3 months, except cannabis or alcohol use disorder, mild;
diagnosis of autism spectrum disorder, pervasive developmental disorder, obsessive-compulsive disorder, post-traumatic stress disorders, Tourette's syndrome
any contraindication to MRI scanning;
history of major neurological disorder (e.g, epilepsy), or head trauma with \> 10 minutes loss of consciousness;
intellectual disability (IQ less than or equal to 70), as determined by the Weschler Abbreviated Scale of Intelligence (WASI);
previous participation in any mindfulness-based treatment;
initiating psychotherapy within 2 months prior to screening, or planning to initiate psychotherapy during study participation; if on therapy, frequency and type should remain stable for 2 months prior to enrollment and during study participation;
no current diagnosis of asthma
history of allergic reaction to N-acetylcysteine

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Cincinnati?

Yes, this clinical trial (NCT07464886) has an active research site in Cincinnati, OH that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Depression Treatment Options in Cincinnati, OH

If you're searching for mild depression treatment options in Cincinnati, OH, this clinical trial (NCT07464886) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Cincinnati research site is actively enrolling participants for this phase 3 clinical trial. You'll receive care from experienced mild depression specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild depression clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Cincinnati, OH