Chicago, ILNCT03819608Now EnrollingIRB Ready

Mild Traumatic Brain Injury Clinical Trial in Chicago, IL

Access cutting-edge mild traumatic brain injury treatment through this clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by Northwestern University

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Expert Care in Chicago

Access mild traumatic brain injury specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mild traumatic brain injury treatment provided free

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Check if you qualify for this mild traumatic brain injury clinical trial in Chicago, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Mild Traumatic Brain Injury Study in Chicago

This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing training (APT) when combined with intermittent theta burst stimulation (iTBS), a type of repetitive transcranial magnetic stimulation and (ii) determine how APT + iTBS changes the neurocognitive system of attention in individuals with persistent attention deficits related to mTBI +/- PTSD.

Sponsor: Northwestern University

Who Can Participate

Inclusion Criteria

At least 18 years of age and no older than 80 years of age
3 months post exposure to mTBI event
Have a history of mTBI with PTSD OR mTBI without PTSD as defined by formalized measures to classify mTBI based on the Symptom Attribution and Classification Algorithm (SACA) and the PTSD Module L of the SCID
Endorse at least moderate severity on at least one of the four cognitive complaints in the Neurobehavioral Symptom Inventory

Exclusion Criteria

Participating in another research study
Non-fluent in English (speaking and reading)
History of epilepsy pre-injury
Receiving antiepileptic treatment for documented active seizures in the past 6 months
Taking medications that lower seizure threshold including antipsychotics, trazodone and tramadol
History of surgery on blood vessels in brain and/or valves of the heart
History of brain hemorrhage, neurovascular conditions and neurodegenerative disorders
History or current diagnosis of psychotic spectrum disorders (i.e. bipolar, schizophrenia)
Significant heart disease as determined by physician review of medical chart
Pregnant at time of enrollment or any time during study participation
MRI or TMS/iTBS contraindications such as claustrophobia, metal in eyes/face or brain
Cardiac pacemakers/defibrillators, cochlear implants, nerve stimulators, intracranial metal clips
Diagnosis of moderate or severe TBI (loss of consciousness \> 30 minutes, alteration of consciousness \> 24 hours, post traumatic amnesia or neuropsychological testing results
Prescribed dosage of mental health medications have been altered within the month preceding study screening. Any participant whose mental health medication(s) has/have changed, within 30 days of study screening. The following are considered a medication change: the addition of or discontinuation of medication, a change in the dose or dosage (daily amount) of medication.
Taking prescribed CNS stimulants and choosing to not stop these medications during study participation
Taking prescribed CNS stimulants and choosing to not stop these medications during study participation
Testing positive for opiates and do not have a prescription for opiates. If on prescription opiates and taking more than the equivalent of 200 mg of morphine per day.
Questionably valid test performance as indicated by a score of ≤ 85% on the Immediate Recognition, Delayed Recognition or Consistency Scales of the Medical Symptom Validity Test (MSVT) and clinical determination of questionable performance validity by a neuropsychologist on the research team
Actively suicidal as evidenced by plan to harm or recent attempt communicated on the Structured Clinical Interview for DSM-V (SCID-5).
Increased Intracranial Pressure (ICP) as evidenced through a funduscopic evaluation or on the baseline MRI scan.
Moderate or severe cannabis use disorder defined by ≥ 4 symptoms on the SCID-5
Severe alcohol use disorder defined by ≥ 6 symptoms on the SCID-5
Baseline systolic BP greater or equal to 170

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT03819608) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mild Traumatic Brain Injury Treatment Options in Chicago, IL

If you're searching for mild traumatic brain injury treatment options in Chicago, IL, this clinical trial (NCT03819608) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mild traumatic brain injury specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mild traumatic brain injury clinical trials near you to find additional studies recruiting in your area.

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