Los Angeles, CANCT04029337Now EnrollingIRB Ready

Mitral Regurgitation Clinical Trial in Los Angeles, CA

Access cutting-edge mitral regurgitation treatment through this clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by HighLife SAS

Quick Self-Assessment

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Expert Care in Los Angeles

Access mitral regurgitation specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related mitral regurgitation treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this mitral regurgitation clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Mitral Regurgitation Study in Los Angeles

Study to evaluate the feasibility, safety and performance of the HighLife trans-septal Transcatheter Mitral Valve in patients with moderate-severe and severe mitral regurgitation who are at high risk for surgical treatment.

Sponsor: HighLife SAS

Who Can Participate

Inclusion Criteria

Age ≥ 18 years
Severe mitral regurgitation
New York Heart Association (NYHA) Functional Class II, III or ambulatory IV.
Patient is under maximally tolerated GDMT (incl. CRT) for at least 3 months
Multidisciplinary Heart Team consensus that the patient is inoperable or at high-risk for surgical repair/replacement due to significant co-morbid conditions
Multidisciplinary Heart Team consensus that the patient is not a suitable candidate for other approved percutaneous repair therapy due to anatomical or medical conditions
Patient meets the anatomical criteria for HighLife valve sizing as determined by CT and TEE Main

Exclusion Criteria

Mitral stenosis
Rheumatic valve disease
Severe calcifications of the mitral annulus and/or mitral leaflets
Prior surgical or interventional treatment of the mitral valve
Unsuitable anatomy for the transapical access
Unsuitable anatomy of the aorta and ilio-femoral vessels for the transfemoral access
Untreated clinically significant coronary artery disease requiring revascularization
LVEF \< 30%
LVEDD \> 70mm
Echocardiographic evidence of intracardiac mass, thrombus or vegetation
Hypertrophic Obstructive Cardiomyopathy (HOCM)
Any surgical or interventional procedure (including PCI) done in the past 30 days prior to procedure

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT04029337) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Mitral Regurgitation Treatment Options in Los Angeles, CA

If you're searching for mitral regurgitation treatment options in Los Angeles, CA, this clinical trial (NCT04029337) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this clinical trial. You'll receive care from experienced mitral regurgitation specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all mitral regurgitation clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA