Chicago, ILNCT06062888Now EnrollingIRB Ready

Moderate to Severe Traumatic Brain Injury Clinical Trial in Chicago, IL

Access cutting-edge moderate to severe traumatic brain injury treatment through this phase 2/3 clinical trial at a research site in Chicago. Study-provided care at no cost to qualified participants.

Sponsored by Northwestern University

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Expert Care in Chicago

Access moderate to severe traumatic brain injury specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related moderate to severe traumatic brain injury treatment provided free

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Check if you qualify for this moderate to severe traumatic brain injury clinical trial in Chicago, IL

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chicago

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chicago site if eligible
  4. 4Begin participation

About This Moderate to Severe Traumatic Brain Injury Study in Chicago

The goal of this clinical trial is to learn about treatment with fresh frozen plasma (FFP) in individuals with moderate to severe traumatic brain injury. The two main question\[s\]it aims to answer are: * Is the FFP treatment safe? * Does the FFP treatment impact the 24-hour, 3-month and 6-month outcomes, intensive-care free days, mortality, and hospital brain and physical function at discharge. Patients with moderate to severe TBI will randomly receive either: * Standard of care treatment * Standard of care treatment + 2 units of FFP. Researchers will compare participants receiving standard of care treatment to those receiving experimental fresh frozen plasma (FFP) treatment to see if the FFP is safe and beneficial to participant outcomes.

Sponsor: Northwestern University

Who Can Participate

Inclusion Criteria

Male or female between the ages of 18 and 65 years
Moderate to severe TBI: GCS 3-12
Cerebral trauma confirmed on the initial CT scan with radiographic findings consistent with Brain Injury Guidelines category 3 (BIG 3).
The potential participant's wallet, when present, was examined and no power of attorney related to blood product administration was identified.

Exclusion Criteria

Persons with a known history of adverse reaction to plasma products.
Persons with a known history of congestive heart failure, renal failure, liver failure, or severe respiratory dysfunction requiring home use of supplemental oxygen.
Persons who are currently incarcerated.
Persons with inadequate venous access.
Treatment cannot start within 1 hour of arrival at the hospital.
The time of injury is unknown.
Non-survivable injuries in the estimation of the attending trauma and/or neurosurgeon.
Interfacility transfers
Class 3 hemorrhagic shock
Persons with known "do not resuscitate" orders prior to randomization
Persons who refuse the administration of blood products
Persons with a research "opt out" bracelet
Persons who require FFP for any other indication (e.g., reversal of coagulopathy)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chicago?

Yes, this clinical trial (NCT06062888) has an active research site in Chicago, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Moderate to Severe Traumatic Brain Injury Treatment Options in Chicago, IL

If you're searching for moderate to severe traumatic brain injury treatment options in Chicago, IL, this clinical trial (NCT06062888) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chicago research site is actively enrolling participants for this phase 2/3 clinical trial. You'll receive care from experienced moderate to severe traumatic brain injury specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all moderate to severe traumatic brain injury clinical trials near you to find additional studies recruiting in your area.

More Traumatic Brain Injury Trials in Chicago, IL

See all traumatic brain injury clinical trials recruiting in Chicago — not just this study.

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Secure · Expert Care · Chicago, IL