Los Angeles, CANCT06417190Now EnrollingIRB Ready

Muscle-Invasive Bladder Carcinoma Clinical Trial in Los Angeles, CA

Access cutting-edge muscle-invasive bladder carcinoma treatment through this phase 2 clinical trial at a research site in Los Angeles. Study-provided care at no cost to qualified participants.

Sponsored by Leslie Ballas

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Expert Care in Los Angeles

Access muscle-invasive bladder carcinoma specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related muscle-invasive bladder carcinoma treatment provided free

Apply for This Los Angeles Location

Check if you qualify for this muscle-invasive bladder carcinoma clinical trial in Los Angeles, CA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Los Angeles

    Convenient for CA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Los Angeles site if eligible
  4. 4Begin participation

About This Muscle-Invasive Bladder Carcinoma Study in Los Angeles

This is a Phase II, single cohort study designed to evaluate outcomes in patients with muscle invasive bladder cancer (MIBC) with variant histology who receive neoadjuvant chemotherapy (NAC) with or without immunotherapy (IO) followed by trimodal therapy (TMT). Enrolled patients will undergo at least 3 cycles of NAC +/- IO (oncologist's choice) followed by a four- or six-week course of concurrent standard of care chemotherapy and radiation therapy. These patients will be compared with historical controls of patients with a diagnosis of pure urothelial carcinoma who have undergone TMT. This study has been designed to test the hypothesis that variant histology TMT can be delivered within 45 days of NAC +/- IO and is therefore a viable option in patients who are risk of systemic disease spread.

Sponsor: Leslie Ballas

Who Can Participate

Inclusion Criteria

Documented diagnosis of MIBC with variant histology, cT2-T4N0M0, confirmed by TURBT and CT C/A/P and/or PET.
Written informed consent obtained from subject and ability for subject to comply with the requirements of the study.

Exclusion Criteria

Evidence of diffuse cis on pathology
Presence of bilateral hydronephrosis (if hydronephrosis is present, can only be unilateral)
Prior radiotherapy to the pelvis
History of systemic therapy for MIBS
Presence of concurrent cancer (remote history of cancer (\>5 years) allowed if the patient is without evidence of disease)

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Los Angeles?

Yes, this clinical trial (NCT06417190) has an active research site in Los Angeles, CA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Muscle-Invasive Bladder Carcinoma Treatment Options in Los Angeles, CA

If you're searching for muscle-invasive bladder carcinoma treatment options in Los Angeles, CA, this clinical trial (NCT06417190) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Los Angeles research site is actively enrolling participants for this phase 2 clinical trial. You'll receive care from experienced muscle-invasive bladder carcinoma specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all muscle-invasive bladder carcinoma clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Los Angeles, CA