Nashville, TNNCT05999630Now EnrollingIRB Ready

Nasolacrimal Duct Obstruction Clinical Trial in Nashville, TN

Access cutting-edge nasolacrimal duct obstruction treatment through this clinical trial at a research site in Nashville. Study-provided care at no cost to qualified participants.

Sponsored by Vanderbilt University Medical Center

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Expert Care in Nashville

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IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related nasolacrimal duct obstruction treatment provided free

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Why Participate?

  • No-Cost Study Care

  • Local to Nashville

    Convenient for TN residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Nashville site if eligible
  4. 4Begin participation

About This Nasolacrimal Duct Obstruction Study in Nashville

The association of radioiodine therapy for the treatment of thyroid cancer with nasolacrimal duct obstruction has been well documented in the medical literature. Prior case reports have documented radioactive iodine detection in the tears of patients following radioiodine therapy. It is possible that radioactive uptake by the cells in the lacrimal sac and nasolacrimal duct lead to inflammation, fibrosis, and obstruction of the tear duct over time. A recent study has shown that the administration of artificial tears decreases the level of detectable radioiodine in the tears of patients undergoing radioiodine therapy for thyroid cancer. The purpose of this study will be to assess whether administering tears after radioactive iodine therapy for thyroid cancer decreases the incidence of nasolacrimal duct obstruction in the two years following radioactive iodine treatment.

Sponsor: Vanderbilt University Medical Center

Who Can Participate

Inclusion Criteria

Radio-iodine therapy for thyroid cancer
Radioiodine therapy ≥150 mCi
Age 18 or older

Exclusion Criteria

Use of eye drops, other than artificial tears
History of periocular trauma with tear duct involvement/lacrimal gland trauma
History of lacrimal drainage disease: canaliculitis, dacryocystitis
Prior radiotherapy
Current or prior use of chemotherapy drugs (i.e. 5-fluorouracil, docetaxel)
Medical conditions that predispose to NLD stenosis (i.e. sarcoidosis, granulomatosis with polyangiitis, chronic lymphocytic leukemia)
Nasolacrimal duct obstruction at baseline

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Nashville?

Yes, this clinical trial (NCT05999630) has an active research site in Nashville, TN that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Nasolacrimal Duct Obstruction Treatment Options in Nashville, TN

If you're searching for nasolacrimal duct obstruction treatment options in Nashville, TN, this clinical trial (NCT05999630) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Nashville research site is actively enrolling participants for this clinical trial. You'll receive care from experienced nasolacrimal duct obstruction specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all nasolacrimal duct obstruction clinical trials near you to find additional studies recruiting in your area.

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