Evanston, ILNCT06315738Now EnrollingIRB Ready

Necrotizing Enterocolitis Clinical Trial in Evanston, IL

Access cutting-edge necrotizing enterocolitis treatment through this phase 1/2 clinical trial at a research site in Evanston. Study-provided care at no cost to qualified participants.

Sponsored by Noveome Biotherapeutics, formerly Stemnion

Quick Self-Assessment

See if you qualify for this Evanston location

Preparing your pre-screening questions…

Expert Care in Evanston

Access necrotizing enterocolitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related necrotizing enterocolitis treatment provided free

Apply for This Evanston Location

Check if you qualify for this necrotizing enterocolitis clinical trial in Evanston, IL

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Evanston

    Convenient for IL residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Evanston site if eligible
  4. 4Begin participation

About This Necrotizing Enterocolitis Study in Evanston

The primary objective of this study is to determine the safety and tolerability of two dose levels (0.5 mL/kg and 1.0 mL/kg) of once daily (QD) via IV route of administration of ST266 in treating patients with Bell's stage IIA or higher medical NEC by incidence of treatment emergent adverse events (TEAEs) and SAEs, with a secondary objective to assess preliminary efficacy of the same two dose levels (0.5 mL/kg and 1.0 mL/kg) of QD via IV route of administration of ST266 in treating patients with

Sponsor: Noveome Biotherapeutics, formerly Stemnion

Who Can Participate

Inclusion Criteria

Infants born from ≥22 weeks gestational age up to and including 40 weeks gestational age; up to 40 weeks postmenstrual age (gestational age plus chronological age in terms of weeks) with current weight at diagnosis of NEC between ≥500g and ≤3000g, as a result of prematurity and/or IUGR. Parent(s)/legal medical representative(s) voluntarily provides written consent prior to study enrollment.
Bell's Stage IIA or higher medical NEC (Stages IIA - IIIA only) diagnosis by radiologic confirmed pneumatosis intestinalis and may include intestinal dilation and ileus. The clinician confirms NEC diagnosis by evaluation of the radiologic imaging for confirmed pneumatosis intestinalis. If X-ray is used and is equivocal, an ultrasound (US) may be used, if available, to confirm pneumatosis. If the clinician (Neonatologist and/or Pediatric Surgeon) has differing interpretation from that of the Radiologist, that should be documented in both the medical and research records for accuracy of NEC diagnosis.

Exclusion Criteria

Infants with abdominal perforation.
Not expected to survive ≥2 weeks or born with a lethal condition requiring hospice or palliative care (e.g., disease has progressed to NEC totalis, or patient has multi-organ system failure).
Born with major congenital anomalies such as cardiac defects (e.g., Tetralogy of Fallot) or chromosomal disorders/anomalies (e.g., neural tube defect).
Mother's receipt of any investigational product during pregnancy.
Infants with malignancies (e.g., neoplastic cell growth as a solid tumor or a blood neoplasm, such as congenital leukemia).
Infants with hypercoagulability disorders (any active thrombosis, diagnosis of disseminated intravascular coagulation or other acquired/inherited disorders (i.e., hemophilia) of coagulation.
Infants with a known immunodeficiency (such as galactosemia or agranulocytosis).
Infants with anatomic defects that require surgical intervention.
Infants with persistent pulmonary hypertension of newborn.
Infants with any congenital or acquired gastrointestinal pathology that preclude feeds within 7 days after birth (e.g., duodenal atresia).
Infants who have hypoxic ischemic injury (perinatal asphyxia).
Infants with polycythemia (at time of treatment) (\>22 g/dL).
Positive maternal human immunodeficiency virus status.
History of maternal drug abuse (such as amphetamines, opiates, cocaine). This does not include marijuana, or prescription medications for treatment of drug abuse.
Considered by the Investigator, for any reason, to be an unsuitable candidate for the study.
Infants diagnosed with NEC who will require immediate surgical intervention.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Evanston?

Yes, this clinical trial (NCT06315738) has an active research site in Evanston, IL that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Necrotizing Enterocolitis Treatment Options in Evanston, IL

If you're searching for necrotizing enterocolitis treatment options in Evanston, IL, this clinical trial (NCT06315738) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Evanston research site is actively enrolling participants for this phase 1/2 clinical trial. You'll receive care from experienced necrotizing enterocolitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all necrotizing enterocolitis clinical trials near you to find additional studies recruiting in your area.

More Ulcerative Colitis Trials in Evanston, IL

See all ulcerative colitis clinical trials recruiting in Evanston — not just this study.

Browse Ulcerative Colitis Trials in Evanston →

Browse More Trials by Condition

Ulcerative Colitis TrialsAll Conditions →

Ready to Join in Evanston?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · Evanston, IL