NCT07150923 · Children's Hospital of Philadelphia
Supraglottic Airway for Resuscitation Trial
(SUGAR)
What this study is about
This is a hybrid type 3 effectiveness-implementation parallel cluster randomly assigned superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on implementation outcomes.
View original scientific description
This is a hybrid type 3 effectiveness-implementation parallel cluster randomized superiority trial designed to compare two strategies to promote early supraglottic airway (SA) rescue during neonatal resuscitation, with a focus on implementation outcomes.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Employed full-time by the hospital, affiliated practice, or affiliated university in a role that involves newborn resuscitation
- Fluent in English Administrator 1a inclusion criteria
- Oversee the care of newborns on a local level (e.g. nurse manager) or a hospital level (e.g. Chief Quality and Safety Officer)
- Fluent in English Clinical provider and administrator
Exclusion criteria
- 1a criteria: No exclusion criteria Population 1b: Clinical providers who participate in qualitative interviews Clinical provider 1b inclusion criteria:
- Employed full-time by the hospital, affiliated practice, or affiliated university in a role that involves newborn resuscitation
- Fluent in English Clinical provider 1b exclusion criteria: No exclusion criteria Population 2: Patients who receive neonatal resuscitation at birth Inclusion Criteria:
- Inborn (not transferred to the hospital after birth)
- ≥34 weeks' gestation at birth, based on best obstetrical estimate
- Received PPV during neonatal resuscitation (as per provider's clinical assessment) Exclusion Criteria:
- Congenital diaphragmatic hernia
- Airway anomalies
Where
- Birmingham, Alabama
- Little Rock, Arkansas
- Chula Vista, California
- La Mesa, California
- Los Angeles, California
- Murrieta, California
- Palo Alto, California
- San Diego, California
- Newark, Delaware
- Springfield, Illinois
- Indianapolis, Indiana
- Brunswick, Maine
And 16 more locations — see the full list below.
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 27, 2026 · Source of record for eligibility and locations