Portland, ORNCT06946563Now EnrollingIRB Ready

Neural Tube Defects Clinical Trial in Portland, OR

Access cutting-edge neural tube defects treatment through this clinical trial at a research site in Portland. Study-provided care at no cost to qualified participants.

Sponsored by Oregon Health and Science University

Quick Self-Assessment

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Expert Care in Portland

Access neural tube defects specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related neural tube defects treatment provided free

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Check if you qualify for this neural tube defects clinical trial in Portland, OR

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Portland

    Convenient for OR residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Portland site if eligible
  4. 4Begin participation

About This Neural Tube Defects Study in Portland

This is a single-arm prospective study to record maternal and neonatal outcomes on subjects who undergo fetoscopic repair of Neural Tube Defects (NTD) at Oregon Health \& Science University (OHSU). Fetoscopic repair will take place between 24 weeks 0 days and 27 weeks 6 days gestation. Surgical, post-operative, delivery, and neonatal outcomes will be collected.

Sponsor: Oregon Health and Science University

Who Can Participate

Inclusion Criteria

Maternal age 18 years or older
Capable of consenting for their own participation in the study
Decision to have fetoscopic repair following counseling of all options
Open spina bifida with the upper boundary between T1 and S1
Gestational age between 24 0/7 to 26 6/7 weeks' gestation at the time of surgery
Normal karyotype and/or normal chromosomal microarray by invasive testing. In the case of a microdeletion, microduplication, or variant of uncertain significant, the decision to include or exclude will be at the discretion of the Principal Investigators.
Absence of major cardiac anomalies confirmed by fetal echocardiogram
Adequate social support throughout pregnancy
Parental or guardian willingness to undergo follow-up evaluations of the child after birth

Exclusion Criteria

Multiple gestation
Major fetal anomalies unrelated to the neural tube defect
Kyphosis in fetus of 30 degrees or more as assessed by ultrasound or MRI
Previous spontaneous singleton preterm birth prior to 37 weeks
Presence of cervical cerclage at the time of surgery or history of cervical insufficiency
Cervical length less than 20 mm by endovaginal ultrasound
Placenta previa or evidence of placental abruption
Technical factors such as large uterine fibroids, uterine anomalies, or fetal membrane separation for which the risks of surgery are deemed to outweigh the benefits
Maternal obesity precluding surgical access with a BMI \> 45 or if the Principal Investigator determines the body habitus to be technically challenging
Alloimmunization in pregnancy including Kell sensitization or a history of neonatal alloimmune thrombocytopenia
Maternal HIV or Hepatitis B positive status. If the patient's HIV or Hepatitis B status is unknown, the patient must be tested and found to be negative prior to surgery
Known Hepatitis C positivity. If the patient's Hepatitis C status is known, they do not need to be screened
Maternal medical condition which is a contraindication to surgery or general anesthesia. This includes previous hysterotomy in the active segment of the uterus
Maternal medical co-morbidities which would significantly increase the risk of spontaneous or iatrogenic preterm delivery
Inability of the patient to comply with travel and follow-up requirements of the study
Patient not meeting psychosocial criteria determined by fetal care social worked to comply with the medical care and plan for follow ups
Participation in another interventional study that influences maternal and fetal morbidity and mortality
Known history of hypersensitivity to collagen products or chondroitin materials

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Portland?

Yes, this clinical trial (NCT06946563) has an active research site in Portland, OR that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Neural Tube Defects Treatment Options in Portland, OR

If you're searching for neural tube defects treatment options in Portland, OR, this clinical trial (NCT06946563) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Portland research site is actively enrolling participants for this clinical trial. You'll receive care from experienced neural tube defects specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all neural tube defects clinical trials near you to find additional studies recruiting in your area.

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