NCT06029075 · The University of Texas Health Science Center, Houston
tACS for Neuropathic Pain Management After SCI
What this study is about
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
View original scientific description
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Exclusion criteria
- for SCI subjects Inclusion criteria: A patient who
- has neuropathic pain after traumatic spinal cord injury or amputation or brain injury;
- has chronic pain, \>3 months;
- is between 18 to 75 years of age;
- is stable on oral pain medications at least two weeks. Patients are allowed to continue their pain medications, i.e., no change in pain medications. NOTE: we plan to begin the study with the spinal cord injury (SCI) subject population as a cohort first, then expand to other subject populations Exclusion criteria: Patients will be excluded if they
- are currently adjusting oral pain medications for their neuropathic pain;
- have pain, but not neuropathic, e.g., from inflammation at the incision wound of the residual limb or neuroma;
- have a pacemaker metal implants or supplemental oxygen;
- have amputation in their arm(s);
- fail to have a motor contraction in the arm muscles with TMS;
- are not able to follow commands, or to give consent;
- have asthma or other pulmonary disease;
- are not medically stable;
- have preexisting psychiatric disorders;
- alcohol or drug abuse.
Where
- Houston, Texas
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Jun 3, 2026 · Source of record for eligibility and locations