Lubbock, TXNCT06817018Now EnrollingIRB Ready

Neuropathic Pain Clinical Trial in Lubbock, TX

Access cutting-edge neuropathic pain treatment through this clinical trial at a research site in Lubbock. Study-provided care at no cost to qualified participants.

Sponsored by Leslie Shen

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Expert Care in Lubbock

Access neuropathic pain specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related neuropathic pain treatment provided free

Apply for This Lubbock Location

Check if you qualify for this neuropathic pain clinical trial in Lubbock, TX

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Lubbock

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Lubbock site if eligible
  4. 4Begin participation

About This Neuropathic Pain Study in Lubbock

Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain mechanisms. The previous study reported that ginger root extract supplementation palliated pain-spectrum behaviors in animals with neuropathic pain via the microbiota-gut-brain axis. The proposed study is primarily designed to use ginger supplementation for a better understanding of the role of microbiota-gut-brain interactions in sciatica states in a randomized, double-blinded, and placebo-controlled trial. Eighty participants with sciatica will be randomized to receive placebo (2000 mg starch daily) or ginger (2000 mg daily) for 8 weeks. This study will evaluate the effects of ginger supplementation on gut function measured as gut microbiota composition using 16S rRNA sequencing analysis, intestinal permeability based on plasma lipopolysaccharide binding protein and fecal zonulin using ELISA, and fecal metabolites using LC-MS/MS analysis (SA 1); on neuroinflammation in whole blood mRNA using nCounter® Neuroinflammation Panels analysis (SA 2); and on pain-associated outcomes and brain neuroplasticity by assessing functional (resting state-fMRI) and structural (Diffusion Tensor Imaging) connectivity (SA 3).

Sponsor: Leslie Shen

Who Can Participate

Inclusion Criteria

18-85 years old men and women with BMI \< 25 or ≥ 30 kg/m2
low back or gluteal pain radiating into leg(s) past the knee (sciatica) with pain duration of at least 3 months (chronic sciatica)
pain scale \> 3 out of 10 (0=no pain,10=worst pain imaginable) during the past 24 hours
willingness to accept randomization.
woman of childbearing potential agrees to use an effective form of contraception during the study

Exclusion Criteria

Sciatica aspects:
known or suspected serious spinal pathology (e.g., cauda equina syndrome or spinal fracture)
scheduled, or being considered, for spinal surgery or interventional procedures for sciatica during study period
focal neurological deficits with progressive or disabling symptoms
low back pain without sciatica GI aspects:
unstable GI disorder
history of chronic or systemic autoimmune diseases with GI involvement
recent (\<1 month) appearance of diarrhea or hematochezia before study begins
recent (\<1 month) exposure to antibiotics before study start Other exclusion considerations:
pregnant or breast-feeding women
women of child-bearing potential will have a urine pregnancy test done prior to the baseline MRI and administration of any study drug. The clinical research coordinator will run the pregnancy test and inform the patient of the results. If the test is positive, they will be withdrawn from study participation.
cognitive impairment, history of psychiatric conditions indicating mental health instability or incapacity
likeliness of moving during the trial, lack of transportation, or unavailability at sample collection times.
presence of a bleeding diathesis
taking anticoagulant medications (e.g Heparin, Warfarin)
taking dual antiplatelet medications (e.g. aspirin + Plavix)
participants with clinically significant laboratory abnormalities of liver function (AST and ALT) and kidney function (BUN and serum creatinine) abnormalities. Definition of clinically significant for liver function is AST/ALT ≥ 3.0x ULN and for kidney function is serum creatinine \> 2.0 mg/dl and BUN \> 1.5x ULN.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Lubbock?

Yes, this clinical trial (NCT06817018) has an active research site in Lubbock, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Neuropathic Pain Treatment Options in Lubbock, TX

If you're searching for neuropathic pain treatment options in Lubbock, TX, this clinical trial (NCT06817018) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Lubbock research site is actively enrolling participants for this clinical trial. You'll receive care from experienced neuropathic pain specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all neuropathic pain clinical trials near you to find additional studies recruiting in your area.

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