Austin, TXNCT07763197Now EnrollingIRB Ready

Non-Muscle Invasive Bladder Cancer Clinical Trial in Austin, TX

Access cutting-edge non-muscle invasive bladder cancer treatment through this clinical trial at a research site in Austin. Study-provided care at no cost to qualified participants.

Sponsored by Natera, Inc.

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Expert Care in Austin

Access non-muscle invasive bladder cancer specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related non-muscle invasive bladder cancer treatment provided free

Apply for This Austin Location

Check if you qualify for this non-muscle invasive bladder cancer clinical trial in Austin, TX

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Why Participate?

  • No-Cost Study Care

  • Local to Austin

    Convenient for TX residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Austin site if eligible
  4. 4Begin participation

About This Non-Muscle Invasive Bladder Cancer Study in Austin

The SCORE-NMIBC study is a prospective, multi-center, study designed to collect data and biological samples from participants diagnosed with non-muscle Invasive Bladder Cancer (NMIBC). Study participants will undergo research blood and urine collections, as well as tumor tissue collected as part of a standard-of-care procedure(s), for use in research. Collected samples and data will be analyzed to evaluate biomarkers associated with development and validation of cancer monitoring and detection assays ("Natera cancer monitoring and detection test(s)").

Sponsor: Natera, Inc.

Who Can Participate

Inclusion Criteria

Patient is at least 18 years of age or older.
Eastern Cooperative Oncology Group performance status ≤ 2.
Patient has a suspected high risk non-muscle invasive bladder cancer. Note: The AUA/SUO risk stratification for primary non-muscle invasive bladder cancer will be used to determine high risk of tumor progression based on clinic and pathologic prognostic factors (Holzbeierlein et al., 2024):
High grade T1.
Any recurrent, High-grade TA.
High grade TA, \>3 cm (or multifocal).
BCG failure in high grade patient.
Any variant histology.\
\*e.g. Micropapillary, plasmacytoid, small cell/neuroendocrine, and sarcomatoid histologies (in pure or mixed form with associated urothelial carcinoma)
Any lymphovascular invasion.
Any high grade prostatic urethral invasion.
Meet the following criteria: a. Cohort A: i. Participant has high risk ≤ T1 bladder cancer and is eligible for intravesical therapy or cystectomy. ii. Participant has been treated with intravesical and/or systemic therapy for high risk ≤ T1 bladder cancer and is entering surveillance. b. Cohort B i. Participant has high risk ≤ T1 bladder cancer and undergoing primary treatment with cystectomy. ii. Patients undergoing cystectomy following recurrence or progression of high risk ≤ T1 bladder cancer and where ≤ T1 bladder cancer is confirmed on cystectomy surgical pathology.
Willing and able to tolerate blood draws according to Natera standard process.
Willing to provide urine collection samples.
Able to consent to and provide residual tumor tissue for research.
Willing and able to comply with the study requirements.

Exclusion Criteria

Pregnant or breastfeeding.
Prior history and treatment for any cancer (including muscle invasive bladder cancer) within the past year, or if they have any other active cancer, with the exception of participants who have undergone surgical removal of basal or squamous skin cancers, as well as those who have received NMIBC-directed therapy, including those undergoing cystectomy for primary NMIBC or after recurrence/progression of NMIBC.
Diagnosis of \>T1 bladder cancer at time of enrollment.
Tumor tissue unavailable and/or consists only of carcinoma in situ (CIS) disease.
At time of enrollment, has undergone or plans to undergo any ctDNA or utDNA testing to assess MRD, with the exception of one-time comprehensive genomic profiling for therapeutic drug selection.
History of bone marrow or organ transplant.
Serious medical conditions that may adversely affect ability to participate in the study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Austin?

Yes, this clinical trial (NCT07763197) has an active research site in Austin, TX that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Non-Muscle Invasive Bladder Cancer Treatment Options in Austin, TX

If you're searching for non-muscle invasive bladder cancer treatment options in Austin, TX, this clinical trial (NCT07763197) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Austin research site is actively enrolling participants for this clinical trial. You'll receive care from experienced non-muscle invasive bladder cancer specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all non-muscle invasive bladder cancer clinical trials near you to find additional studies recruiting in your area.

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