Aurora, CONCT03042221Now EnrollingIRB Ready

Non-Small Cell Carcinoma of Lung, TNM Stage 4 Clinical Trial in Aurora, CO

Access cutting-edge non-small cell carcinoma of lung, tnm stage 4 treatment through this clinical trial at a research site in Aurora. Study-provided care at no cost to qualified participants.

Sponsored by University of Colorado, Denver

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Expert Care in Aurora

Access non-small cell carcinoma of lung, tnm stage 4 specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related non-small cell carcinoma of lung, tnm stage 4 treatment provided free

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Check if you qualify for this non-small cell carcinoma of lung, tnm stage 4 clinical trial in Aurora, CO

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Why Participate?

  • No-Cost Study Care

  • Local to Aurora

    Convenient for CO residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Aurora site if eligible
  4. 4Begin participation

About This Non-Small Cell Carcinoma of Lung, TNM Stage 4 Study in Aurora

A comparison of baseline tumor characteristics in oncogene-driven cancers to tumor characteristics after early response to Tyrosine Kinase Inhibitor (TKI) targeted treatment will allow identification of early adaptive mechanisms of cell survival. This will facilitate targeting and termination of these survival/ resistance pathways before they develop with rational combinations of therapeutic agents to improve outcomes.

Sponsor: University of Colorado, Denver

Who Can Participate

Inclusion Criteria

Targetable Oncogene - Biopsy Cohort (includes blood draw)
Carry a diagnosis of locally advanced or stage IV NSCLC responsive to targeted therapies (per current NCCN guidelines)
Aged 18 years or older
Have a histologically confirmed diagnosis of NSCLC harboring an activating mutation responsive to targeted therapy (per NCCN guidelines)
No prior systemic therapy for locally advanced or metastatic disease.
Planned treatment with targeted therapy specific to the oncogene driver mutation.
Patients must have at least one site of measurable disease ≥ 2cm.
Primary disease site or site of metastatic disease must be amenable to biopsy.
Patients must have the ability to understand and willingness to sign an informed consent document. Targetable Oncogene - Blood Draw Only Cohort
Carry a diagnosis of locally advanced or stage IV NSCLC responsive to targeted therapy (per NCCN guidelines)
Aged 18 years or older
Have a histologically confirmed diagnosis of NSCLC harboring an activating mutation responsive to targeted therapy (per NCCN guidelines)
No prior systemic therapy or radiotherapy for metastatic lung cancer (surgery alone permitted)
Planned treatment with targeted therapy specific to the oncogene driver mutation.
Declines repeat biopsy option or does not have tumor site amenable to biopsy.
Patients must have the ability to understand and willingness to sign an informed consent document. Immunotherapy Cohort - Blood Draw Only
Have a histologically confirmed diagnosis of locally advanced or stage IV NSCLC without a treatable activating mutation that would be amenable to targeted therapy AND planned first line treatment with immunotherapy or chemotherapy plus immunotherapy.
Aged 18 years or older
No prior systemic therapy or radiation therapy for lung cancer (surgery alone permitted)
Patients must have the ability to understand and willingness to sign an informed consent document.

Exclusion Criteria

Targetable Oncogene - Biopsy Cohort (includes blood draw)
Concurrent health problem which would preclude tissue biopsy (e.g. hemophilia or other bleeding predisposition).
Patients whose only biopsy source would involve sampling an anatomic area that carries an unacceptably high procedural risk (e.g. pericardium or kidney) as deemed by the treating physician or by a proceduralist performing the biopsy.
Patients whose only biopsy source involves a sample that may not be evaluable due to insufficient genomic material (such as cerebrospinal or ascitic fluid) as deemed by the treating physician. . Targetable Oncogene Cohort and Immunotherapy Cohort - Blood Draw Only
Planned follow up on therapy outside of the University of Colorado Health System
Unwillingness to allow for residual clinical biopsy specimens to be utilized in this study.

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Aurora?

Yes, this clinical trial (NCT03042221) has an active research site in Aurora, CO that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Non-Small Cell Carcinoma of Lung, TNM Stage 4 Treatment Options in Aurora, CO

If you're searching for non-small cell carcinoma of lung, tnm stage 4 treatment options in Aurora, CO, this clinical trial (NCT03042221) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Aurora research site is actively enrolling participants for this clinical trial. You'll receive care from experienced non-small cell carcinoma of lung, tnm stage 4 specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all non-small cell carcinoma of lung, tnm stage 4 clinical trials near you to find additional studies recruiting in your area.

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